Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6737 |
Zaltoprofen
CN100,扎托布洛芬,Soleton |
COX | Immunology/Inflammation; Neuroscience |
Zaltoprofen (Soleton) 是一种非甾体类抗炎剂,具有强大的抗炎作用和对炎性疼痛的止痛作用。它是可口服的COX-2抑制剂,对COX-1和COX-2的IC50值分别为 1.3 和 0.34 μM。 | |||
T30964 |
Clamoxyquin hydrochloride
Clamoxyquin HCl,Clamoxyquin dihydrochloride,CN-17,900-2B,Clamoxyquine hydrochloride,CN 17900-2 B |
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Clamoxyquin hydrochloride is an anti ameba and antidiarrheal drug. It has been used as a veterinary drug to treat salmon infected with brain armyworm. | |||
T82700 |
Cn2 toxin
β-Mammal toxin Cn2 |
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Cn2 toxin为一β类毒素,具有与电压门控钠通道(Nav)的电压感应域结合的能力。 | |||
T0890 |
Mefenamic acid
CN-35355,CI 473,甲芬那酸,甲灭酸 |
COX | Immunology/Inflammation; Neuroscience |
Mefenamic acid (CN-35355) 是一种非甾体抗炎剂,可竞争性抑制hCOX-1和hCOX-2,IC50值分别为 40 nM 和 3 μM。 | |||
T36440 |
GS-441524 tris-isobutyryl ester
|
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GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with an EC50value of 0.26 μM. 1.Mackman, R.L., Hui, H.C., Perron, M., et al.Prodrugs of a 1’-CN-4-aza-7,9-dideazaadenosine C-nucleoside leading to the discovery of remdesivir (GS-5734) as a potent inhibitor of respiratory syncytial virus with efficacy in the african green monkey mode... |