Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10801 |
CHMFL-ABL/KIT-155
CHMFL-ABL-KIT-155 |
c-Kit | Tyrosine Kinase/Adaptors |
CHMFL-ABL/KIT-155 is a highly potent and orally active type II ABL/c-KIT dual kinase inhibitor (IC50s: 46 nM/75 nM). It arrests cell cycle progression and induces apoptosis. |