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Search Results for " cd39 "

Targets Recommended: ATPase Adiponectin receptor

7

抑制剂 & 化合物

7

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T4190	Ticlopidine PCR 5332,Ticlid,噻氯匹定	ATPase; Adiponectin receptor	GPCR/G Protein; Membrane transporter/Ion channel
	Ticlopidine (PCR 5332) 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂，抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂，能够阻断 NTPDase 同工酶，对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。
T10216	AB-680	CD73	Immunology/Inflammation
	AB-680 是一种选择性可逆的CD73(胞外核苷酸酶) 抑制剂，具有抗肿瘤活性。它对 hCD73 的Ki 值为 4.9 pM，对其选择性是对相关胞外核苷酸酶 CD39 的 10000 多倍。
T81510	Perenostobart
	Perenostobart为一人源化免疫球蛋白G4-kappa，针对ENTPD1/CD39的单克隆抗体。该化合物兼具免疫刺激剂与抗肿瘤药物的特性。
T73886	AB-680 ammonium
	AB-680 ammonium 是一种有效、可逆、选择性的 CD73(胞外核苷酸酶) 抑制剂，对 hCD73 的Ki 值为 4.9 pM，对其选择性是对相关胞外核苷酸酶CD39的 10000 多倍。具有抗肿瘤活性。
T14320	ARL67156 trisodium salt	Others	Others
	ARL 67156 is a weak competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively[1]. ARL67156 trisodium salt is an inhibitor of ecto-ATPase.
T73644	ARL67156 trisodium hydrate
	ARL67156 (FPL 67156) trisodium hydrate 是一种ecto-ATPase 抑制剂。ARL67156 trisodium hydrate 是竞争性 NTPDase1 (CD39)，NTPDase3 和 NPP1 抑制剂，Ki 分别为 11，18 和 12 μM。ARL67156 trisodium hydrate 可用于钙化性主动脉瓣疾病、哮喘等疾病的研究。
T73645	ARL67156 triethylamine
	ARL67156 (FPL 67156) triethylamine 是一种ecto-ATPase 抑制剂。ARL67156 triethylamine 是竞争性 NTPDase1 (CD39)，NTPDase3 和 NPP1 抑制剂，Ki 分别为 11，18 和 12 μM。ARL67156 triethylamine 可用于钙化性主动脉瓣疾病、哮喘等疾病的研究。

化合物

Cat.No: T4190

Synonym: PCR 5332,Ticlid,噻氯匹定

Target: ATPase, Adiponectin receptor

Cat.No: T10216

Target: CD73

Cat.No: T81510

AB-680 ammonium

Cat.No: T73886

ARL67156 trisodium salt

Cat.No: T14320

Target: Others

ARL67156 trisodium hydrate

Cat.No: T73644

ARL67156 triethylamine

Cat.No: T73645

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01126	CD39 Protein, Human, Recombinant (His) SPG64,CD39,ectonucleoside triphosphate dip...	Human	Baculovirus Insect Cells
	CD39 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.8 kDa and the accession number is P49961-1.
TMPY-02808	CD39 Protein, Mouse, Recombinant (His) NTPDase-1,AA408691,ectonucleoside triphosphate diphosphohydr...	Mouse	Baculovirus Insect Cells
	CD39 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51 kDa and the accession number is P55772.
TMPY-05151	CD39 Protein, Cynomolgus, Rhesus, Recombinant (His) ectonucleoside triphosphate diphosphohydrolase 1	Cynomolgus,Rhesus	Baculovirus Insect Cells
	CD39 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.8 kDa and the accession number is XP_015311944.1&XP_015003298.1.
TMPH-03283	CD39 Protein, Rat, Recombinant (His) ATP diphosphohydrolase,Entpd1,Nucleoside triphosphate diphos...	Rat	Baculovirus Insect Cells
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPH-03284	CD39 Protein, Rat, Recombinant (E. coli, His) Entpd1,ATP-DPH,Ecto-ATP diphosphohydrolase 1,CD...	Rat	E. coli
	In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.
TMPJ-00682	CD39L1 Protein, Mouse, Recombinant (His) Ectonucleoside triphosphate diphosphohydrolase 2,Entpd2	Mouse	HEK293 Cells
	CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by p...
TMPY-02929	ENTPD2 Protein, Human, Recombinant (aa 29-460, His) ectonucleoside triphosphate diphosphohydrolase 2,NTPDase-2,R...	Human	Baculovirus Insect Cells
	NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in...

重组蛋白

CD39 Protein, Human, Recombinant (His)

Cat.No: TMPY-01126

Species: Human

Expression System: Baculovirus Insect Cells

CD39 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02808

Species: Mouse

Expression System: Baculovirus Insect Cells

CD39 Protein, Cynomolgus, Rhesus, Recombinant (His)

Cat.No: TMPY-05151

Species: Cynomolgus,Rhesus

Expression System: Baculovirus Insect Cells

CD39 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03283

Species: Rat

Expression System: Baculovirus Insect Cells

CD39 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03284

Species: Rat

Expression System: E. coli

CD39L1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00682

Species: Mouse

Expression System: HEK293 Cells

ENTPD2 Protein, Human, Recombinant (aa 29-460, His)

Cat.No: TMPY-02929

Species: Human

Expression System: Baculovirus Insect Cells

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