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Search Results for " cd105 "
Targets Recommended: TGF-beta/Smad Immunology/Inflammation related

1

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T76941 Carotuximab

DE-122,TRC105

TGF-beta/Smad; Immunology/Inflammation related Immunology/Inflammation; Stem Cells
Carotuximab(DE-122)是一种新型内胆苷抗体,具有强大的抗血管生成活性和抗炎活性。Carotuximab 可阻断内皮糖蛋白 (CD105) 及其下游 Smad 信号通路。Carotuximab 具有免疫调节和抗肿瘤作用,可预防高胆固醇血症和高血糖诱导的人内皮功能障碍。

化合物

Carotuximab
Cat.No: T76941
Synonym: DE-122,TRC105
Target: TGF-beta/Smad, Immunology/Inflammation related
Cat. No. Product Name Species Expression System
TMPY-01615 Endoglin/CD105 Protein, Mouse, Recombinant (His)

Endo,CD105,S-endoglin,AI528660,endoglin,AI...

Mouse HEK293 Cells
Endoglin/CD105 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.2 kDa and the accession number is Q63961.
TMPK-00359 Endoglin/CD105 Protein, Human, Recombinant (His & Avi)

CD105,ORW,ORW1,ENG,END,Endoglin,HHT1

Human HEK293 Cells
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response...
TMPY-01384 Endoglin/CD105 Protein, Human, Recombinant (His)

endoglin,HHT1,END,ORW1

Human HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.3 kDa and the accession number is A0A024R878.
TMPJ-00361 Endoglin Protein, Human, Recombinant (Trx & His)

CD105,END,Endoglin,ENG

Human E. coli
Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins an...
TMPY-00783 Endoglin/CD105 Protein, Human, Recombinant (hFc)

END,HHT1,ORW1,endoglin

Human HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.5 kDa and the accession number is A0A024R878.

重组蛋白

Endoglin/CD105 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01615
Species: Mouse
Expression System: HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00359
Species: Human
Expression System: HEK293 Cells
Endoglin/CD105 Protein, Human, Recombinant (His)
Cat.No: TMPY-01384
Species: Human
Expression System: HEK293 Cells
Endoglin Protein, Human, Recombinant (Trx & His)
Cat.No: TMPJ-00361
Species: Human
Expression System: E. coli
Endoglin/CD105 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00783
Species: Human
Expression System: HEK293 Cells
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