Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9638 |
CCT241161
|
Raf | MAPK |
CCT241161 is an orally active pan-RAF inhibitor, with IC50 values of 3, 6, 10, 15, and 30 nM for LCK, CRAF, SRC, V600E-BRAF, and BRAF, respectively. It displays significant activity against BRAF and NRAS mutant melanomas, as well as demonstrating anticancer cell proliferative effects [1]. |