首页工具

登录

搜索结果

Search Results for " ccr8 "

Targets Recommended: CCR

10

抑制剂 & 化合物

5

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T9983	CCR8 antagonist 1 LUN04765	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR8 antagonist 1 是 C-C Motif 趋化因子受体 8 (CCR8) 的拮抗剂，Ki 值为 1.6 nM。
T62944	CCR8 antagonist 2
	CCR8 antagonist 2 是一种 CCR8 的有效拮抗剂，能够抑制的 CCR8 活性。CCR8 (C-C Motif 趋化因子受体 8) 主要表达于 Treg 细胞和 Th2 细胞，且不在 Th1 细胞上表达。CCR8 antagonist 2 能够用于由 CCR8 介导的疾病（如癌症和/或神经性疼痛）的治疗。
T10425	AZ084	CCR	Immunology/Inflammation; Microbiology/Virology
	AZ084 是可口服的选择性 CCR8变构拮抗剂，其Ki 值为 0.9 nM，可研究哮喘。
T3360	ZK 756326 ZK756326 2HCl	CCR	Immunology/Inflammation; Microbiology/Virology
	ZK 756326 是一种选择性的非肽 CCR8 趋化因子受体激动剂（IC50：1.8 μM，在人体内；2.6 μM，在小鼠体内）。对 CCR4/5 和 CXCR3/4 没有活性，比其他 26 种 GPCR 的选择性高 28 倍（对 α2A 和 5-HT 受体的选择性较低）。诱导趋化性并抑制 Env 介导的 (HIV) 细胞-细胞融合。
T24700	R243 R 243,R-243	CCR	Immunology/Inflammation; Microbiology/Virology
	R243 是选择性的CCR8拮抗剂，可抑制CCL1/CCR8的相互作用，以及CCR8信号传导和趋化性，具有抗伤害感受和抗炎作用。
T16111	ML604086	CCR	Immunology/Inflammation; Microbiology/Virology
	ML604086 是选择性CCR8抑制剂，抑制循环T 细胞上 CCL1 与 CCR8 结合，还抑制 CCL1 介导的趋化性并提高细胞内 Ca2 浓度。
T79095	SB-649701	CCR	Immunology/Inflammation; Microbiology/Virology
	SB-649701为一种高效的人源CCR8拮抗剂，具有pIC50值7.7。AZ084则常被用于哮喘研究。
T11862	LMD-009	Others	Others
	LMD-009 mediates chemotaxis, inositol phosphate accumulation, and calcium release in high potencies with EC50s from 11 to 87 nM. LMD-009 is a selective CCR8 nonpeptide agonist.
T68564	LMD-A
	LMD-A, also known as CCR8 antagonist LMD-A, is a CCR8 antagonist.
T79096	IPG7236	CCR	Immunology/Inflammation; Microbiology/Virology
	IPG7236为选择性CCR8拮抗剂，于人乳腺癌小鼠异种移植模型中展现显著肿瘤抑制效果，适用于癌症研究。

化合物

CCR8 antagonist 1

Cat.No: T9983

Synonym: LUN04765

Target: CCR

CCR8 antagonist 2

Cat.No: T62944

Cat.No: T10425

Target: CCR

Cat.No: T3360

Synonym: ZK756326 2HCl

Target: CCR

Cat.No: T24700

Synonym: R 243,R-243

Target: CCR

Cat.No: T16111

Target: CCR

Cat.No: T79095

Target: CCR

Cat.No: T11862

Target: Others

Cat.No: T68564

Cat.No: T79096

Target: CCR

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00896	CCR8 Protein, Human, Recombinant (hFc) GPR-CY6,CKR-L1,CMKBRL2,ChemR1,CDw198,CCR-<...	Human	HEK293 Cells
	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 30.62 kDa and the accession number is P51685-1.
TMPK-00897	CCR8 Protein, Human, Recombinant (mFc) GPR-CY6,CY6,CKRL1,CMKBRL2,TER-1,CDw198,CCR...	Human	HEK293 Cells
	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 30.25 kDa and the accession number is P51685-1.
TMPK-01316	CCR8 Protein, Cynomolgus, Recombinant (mFc) GPR-CY6,CY6,CKRL1,CDw198,CMKBR8,ChemR1,CKR...	Cynomolgus	HEK293 Cells
	CC chemokine receptor (CCR) 8 (previously called CKR-L1 or TER1 and designated CD198), which is expressed on Th2 cells and eosinophils, has been implicated in allergic diseases. CCR8 may regulate monocyte chemotaxis and thymic cell line apoptosis and is alternative coreceptor with CD4 for HIV-1 infection. CCR8 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 29.73 kDa and the accession number is A0A8J8XUI3.
TMPY-00641	LEC/CCL16 Protein, Human, Recombinant (His) SCYL4,HCC-4,ILINCK,LMC,SCYA16,NCC-4,CKb12,Mtn-1,LCC-1,LEC,ch...	Human	E. coli
	CCL16, a chemokine poorly characterized at the functional level. Human CCL16 is a member of the CC family, and its gene maps to human chromosome 17q. In the mouse, only a pseudogene has been identified to date. CCL16 is a functional ligand for CCR1, CCR2, CCR5, and CCR8. Recombinant CCL16 demonstrated chemotactic activity on human monocytes and lymphocytes. Based on the ability of human chemokines to exert activity on and bind to murine receptors, the TSA mouse adenocarcinoma cell line was trans...
TMPJ-00018	CCL16 Protein, Human, Recombinant NCC-4,Lymphocyte and Monocyte Chemoattractant,LMC,NCC4,HCC-4...	Human	E. coli
	CCL16 is a member of CC chemokine family. CCL16 cDNA encodes a 120 amino acid peptide along with a 23 amino acids signal peptide that is cleaved to generate 97 amino acid protein. CCL16 is distantly related to other CC chemokines, showing less than 30% sequence identity. CCL16 elicits its effects on cells by interacting with cell surface chemokine receptors such as CCR1, CCR2, CCR5 and CCR8. Recombinant CCL16 has been shown to chemoattract human monocytes and THP1 cells but not resting lymphocyt...

重组蛋白

CCR8 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00896

Species: Human

Expression System: HEK293 Cells

CCR8 Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00897

Species: Human

Expression System: HEK293 Cells

CCR8 Protein, Cynomolgus, Recombinant (mFc)

Cat.No: TMPK-01316

Species: Cynomolgus

Expression System: HEK293 Cells

LEC/CCL16 Protein, Human, Recombinant (His)

Cat.No: TMPY-00641

Species: Human

Expression System: E. coli

CCL16 Protein, Human, Recombinant

Cat.No: TMPJ-00018

Species: Human

Expression System: E. coli

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼