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Search Results for " ccr6 "

Targets Recommended: CCR

4

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T10715	CCR6 inhibitor 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR6 inhibitor 1是一种有效的选择性CCR6抑制剂(猴子和人类CCR6的IC50分别为0.45和6 nM)。CCR6在自身免疫性疾病和非自身免疫性疾病中都有关联，因此CCR6 inhibitor 1 作为CCR6的小分子抑制剂对体外和体内病理生理学研究都有用。
T60145	CCR6 antagonist 1	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR6 antagonist 1 是一种 CCR6 拮抗剂，可抑制 CCL20/CCR6 信号通路。 CCR6 antagonist 1 可用于自身免疫介导的炎症性疾病的研究，如炎症性肠病 (IBDs)。
T9721	ML339	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	ML339 是有效的CXCR6选择性拮抗剂，IC50为 140 nM。ML339 对 CXCR5，CXCR4，CCR6 和 Apelin 受体 (APJ) 无拮抗作用，IC50>79 μM。ML339 在前列腺癌研究领域有研究的价值。
T73005	PF-07054894
	PF-07054894 是一种有效的 CCR6拮抗剂。 PF-07054894 靶向 G 蛋白偶联受体 (GPCR)。 PF-07054894 可用于炎症性肠病的研究。

化合物

CCR6 inhibitor 1

Cat.No: T10715

Target: CCR

CCR6 antagonist 1

Cat.No: T60145

Target: CCR

Cat.No: T9721

Target: CXCR

Cat.No: T73005

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-01066	CCR6 Protein, Human, Recombinant (His & Myc) GPRCY4,Chemokine receptor-like 3,C-C chemokine receptor type...	Human	E. coli
	CCR6 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 12.9 kDa and the accession number is P51684.
TMPH-02541	Beta Defensin 1/DEFB1 Protein, Mouse, Recombinant (His & SUMO) Beta-defensin 1,BD-1,mBD-1,Defensin, beta 1,Defb1	Mouse	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
TMPH-02544	DEFB4 Protein, Mouse, Recombinant (His & SUMO) Bdef4,BD-4,Beta-defensin 4,Defensin, beta 4,mBD-4,Defb4	Mouse	E. coli
	Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. DEFB4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 20.6 kDa and the accession number is P82019.
TMPH-03101	DEFB1 Protein, Pig, Recombinant (GST) DEFB1,Defensin, beta 1,Beta-defensin 1,BD-1	Sus scrofa (Pig)	E. coli
	Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility. DEFB1 Protein, Pig, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.1 kDa and the accession number is O62697.

重组蛋白

CCR6 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01066

Species: Human

Expression System: E. coli

Beta Defensin 1/DEFB1 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02541

Species: Mouse

Expression System: E. coli

DEFB4 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02544

Species: Mouse

Expression System: E. coli

DEFB1 Protein, Pig, Recombinant (GST)

Cat.No: TMPH-03101

Species: Sus scrofa (Pig)

Expression System: E. coli

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