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Search Results for " ccl12 "
Targets Recommended: CCR TGF-beta/Smad

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T2386 Pirfenidone

S-7701,AMR-69,S-7701,AMR69,吡非尼酮

CCR; TGF-beta/Smad Immunology/Inflammation; Microbiology/Virology; Stem Cells
Pirfenidone (AMR69) 是一种抗纤维化剂,可减弱纤维细胞中CCL2和CCL12的产生。它可抑制细胞生长,并能降低人胶质瘤细胞系中的TGF-β2蛋白水平,具有抗炎活性。
T12485 Pirfenidone-d5

AMR69 D5,Pirfenidone D5

Others Others
Pirfenidone D5 is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells.

化合物

Pirfenidone
Cat.No: T2386
Synonym: S-7701,AMR-69,S-7701,AMR69,吡非尼酮
Target: CCR, TGF-beta/Smad
Pirfenidone-d5
Cat.No: T12485
Synonym: AMR69 D5,Pirfenidone D5
Target: Others
Cat. No. Product Name Species Expression System
TMPY-04671 MCP-5 Protein, Mouse, Recombinant (His)

chemokine (C-C motif) ligand 12,MCP-5,Scya12

Mouse P. pastoris (Yeast)
Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impaired fibronectin and collagen deposition and indirectly stimulated collagen degradation through upregulation of matrix metalloproteinase-2. In post-MI patients, circulating LPS levels strongly associated with the Ccl12 homologue monocyte chemotactic protein 1 (MCP-1). Both MCP-1 ...

重组蛋白

MCP-5 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04671
Species: Mouse
Expression System: P. pastoris (Yeast)
TargetMol Loading
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