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Cat. No. Product Name Target Signaling Pathways
T12346 CBP/p300-IN-5

P300/CBP-IN-5

Epigenetic Reader Domain Chromatin/Epigenetic
P300/CBP-IN-5 is a potent inhibitor of p300/CBP histone acetyltransferase (IC50 of 18.8 nM).
T36626 Lys-CoA

Selective p300 histone acetyltransferase (HAT) inhibitor (IC50 = 50-500 nM). Exhibits approximately 100-fold selectivity for p300 over PCAF (IC50 = 200 μM). Inhibits p300-dependent transcription. Active in vivo. Lau et al (2000) HATs off: selective synthetic inhibitors of the histone acetyltransferases p300 and PCAF. Mol.Cell. 5 589 PMID:10882143 |Liu et al (2008) The structural basis of protein acetylation by the p300/CBP transcriptional coactivator. Nature. 451 846 PMID:18273021 |Burns et al (...

化合物

CBP/p300-IN-5
Cat.No: T12346
Synonym: P300/CBP-IN-5
Target: Epigenetic Reader Domain
Lys-CoA
Cat.No: T36626
Synonym:
Target:
TargetMol Loading
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