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Cat. No. | Product Name | Target | Signaling Pathways |
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T0106 |
Methazolamide
L584601,醋甲唑胺,CL 8490 |
Carbonic Anhydrase | Metabolism |
Methazolamide (CL 8490) 是一种磺胺衍生物,用作碳酸酐酶 (carbonic anhydrase) 抑制剂,对人 carbonic anhydrase II 的 Ki=为 14 nM。它是降低眼压的药物,能够抑制由青光眼及其他眼病引起的眼压升高的作用。 | |||
T73030 |
hCAIX-IN-14
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hCAIX-IN-14 是一种有效的人类CA IX 抑制剂,Ki 值为 134.8 nM。 | |||
T61842 | Carbonic anhydrase inhibitor 14 | ||
Carbonic anhydrase inhibitor 14 (Compound 8b) is a potent CA inhibitor, exhibiting K i values of 1203, 99.7, 9.4, and 27.7 nM against hCA I, hCA II, hCA IX, and hCA XII, respectively. Additionally, it effectively inhibits CDK2 with an IC 50 of 20.3 μM. Furthermore, Carbonic anhydrase inhibitor 14 demonstrates significant antitumor activity [1]. | |||
T76021 | Myelin Basic Protein TFA | ||
Myelin Basic Protein (MHP4-14) TFA 是一种合成肽,包含髓鞘碱性蛋白的残基4-14,是一种非常有选择性的 PKC 底物 (Km=7 μM)。Myelin Basic Protein TFA 不被环腺苷酸依赖性蛋白激酶、酪蛋白激酶 I 和 II、Ca2+/钙调素依赖性蛋白激酶 II 或磷酸化酶激酶磷酸化,可常规用于测定粗组织提取物中低背景的蛋白激酶 C。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T8288 |
14-Deoxyandrographolide
去氧穿心莲内酯,14-去氧穿心莲内酯 |
Apoptosis; Others | Apoptosis; Others |
14-Deoxyandrographolide 是穿心莲中的一种天然产物,是一种钙通道阻断剂,具有保肝功效。它通过诱导 TNFRSF1A 的释放,使肝细胞对 TNF-α 介导的凋亡脱敏。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00967 |
Carbonic Anhydrase 14 Protein, Human, Recombinant (His)
CAXiV,CA14,carbonic anhy... |
Human | HEK293 Cells |
Carbonic Anhydrase 14 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is A8K3J4. |