首页工具

登录

搜索结果

Search Results for " c1s "

5

抑制剂 & 化合物

15

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T74816	Complement C1s-IN-1
	Complement C1s-IN-1 是一种有效的、选择性的、具有口服活性并可穿过血脑屏障的C1s 抑制剂，IC50值为 36 nM。
T10969	DC1SMe	Others	Others
	DC1 is an ADC cytotoxin, similar to the small groove-binding DNA alkylating agent CC-1065. DC1 can be used to synthesize antibody-drug conjugates targeted to the treatment of cancer. DC1Sme is a DC1 derivative with IC50 values of Ramos, Namalwa, HL60 / s
T13568L	BCX 1470 hydrochloride BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl	Serine Protease; Complement System	Immunology/Inflammation; Proteases/Proteasome
	BCX 1470 hydrochloride 是一种高效的丝氨酸蛋白酶抑制剂，具有抗炎活性，能抑制 factor D 和 C1s 的酯水解和溶血活性，可用于研究水肿。
T13568	BCX 1470	Serine Protease	Proteases/Proteasome
	BCX 1470 inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.
T13567	BCX 1470 methanesulfonate	Serine Protease	Proteases/Proteasome
	BCX 1470 methanesulfonate inhibits the esterolytic activity of factor D and C1s (IC50: 96 nM and 1.6 nM), 3.4- and 200-fold better than that of trypsin, respectively.

化合物

Complement C1s-IN-1

Cat.No: T74816

Cat.No: T10969

Target: Others

BCX 1470 hydrochloride

Cat.No: T13568L

Synonym: BCX 1470 hydrochloride(217099-43-9 Free base),BCX1470 HCl

Target: Serine Protease, Complement System

Cat.No: T13568

Target: Serine Protease

BCX 1470 methanesulfonate

Cat.No: T13567

Target: Serine Protease

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-06585	C1s Protein, Human, Recombinant (His) complement component 1, s subcomponent,C1s,FLJ44757	Human	HEK293 Cells
	Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex composed of the binding protein C1q and two proenzymes, C1r and C1s. Upon binding of IgG to the head of C1q, C1r undergoes autoactivation and in turn cleaves and activates C1s. C1r and C1s, the proteases responsible for activation and proteolytic activity of the C1 complex of complem...
TMPY-00359	C1s-A subcomponent Protein, Mouse, Recombinant (His) C1s,MGC13283,AI255193,C1sa,AA959438,AI3273...	Mouse	HEK293 Cells
	C1s-A subcomponent Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is AAH18319.1.
TMPH-02603	C1SB Protein, Mouse, Recombinant (His & Myc) C1sb,C1s,Gm5077,Complement C1s-1 ...	Mouse	E. coli
	C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
TMPK-01051	BLOC1S2 Protein, Human, Recombinant BLOS2,CEAP11,CEAP,BLOC-1 subunit 2	Human	E. coli
	BLOC1S2 (Biogenesis of lysosome-related organelles complex-1 subunit 2) protein is widely expressed in normal tissue as well as in malignant tumors with a tendency towards lower expression levels in certain subtypes of tumors. On the subcellular level, BLOC1S2 is expressed in an organellar-like pattern and co-localizes with mitochondria.
TMPY-02980	BLOC1S2 Protein, Human, Recombinant (GST) CEAP,CEAP11,BLOS2,biogenesis of lysosomal organelles complex...	Human	E. coli
	BLOC1S2, also known as BLOS2, belongs to the BLOC1S2 family. It is a component of BLOC-1 complex. The BLOC-1 complex is composed of BLOC1S1, BLOC1S2, BLOC1S3, DTNBP1, MUTED, PLDN, CNO/cappuccino and SNAPIN. The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. BLOC1S2 interacts directly with BLOC1S1, BLOC1S3, MUTED, CNO/cappuccino and SNAPIN. It may play a role in cell proliferation. It also plays a role in intracell...
TMPH-02596	C1QA Protein, Mouse, Recombinant (E. coli, His) C1QA,Complement C1q subcomponent subunit A	Mouse	E. coli
	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
TMPH-02597	C1QA Protein, Mouse, Recombinant (His) Complement C1q subcomponent subunit A,C1QA	Mouse	P. pastoris (Yeast)
	C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
TMPY-04137	ATP6V1F Protein, Human, Recombinant (GST) Vma7,ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F,...	Human	E. coli
	ATP6V1F encodes a component of vacuolar ATPase mediating acidification. The cDNA and the genomic sequences of ATP6V1F were cloned successfully for the first time from the Giant Panda (Ailuropoda melanoleuca) using reverse transcription polymerase chain reaction and touchdown-polymerase chain reaction, respectively. Topology prediction showed that there is one protein kinase C phosphorylation site, two Casein kinase II phosphorylation sites, and one N-myristoylation site in the ATP6V1F protein. U...
TMPH-02602	C1RA Protein, Mouse, Recombinant (His & Myc) Complement component 1 subcomponent r-A,C1ra,C1r,Complement ...	Mouse	E. coli
	C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
TMPH-03272	Complement factor D Protein, Rat, Recombinant (His) Adipsin,Df,Adn,C3 convertase activator,Complement factor D,E...	Rat	P. pastoris (Yeast)
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
TMPH-03271	Complement factor D Protein, Rat, Recombinant (His & Myc) Adn,C3 convertase activator,Properdin factor D,Complement fa...	Rat	HEK293 Cells
	Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. Complement factor D Protein, Rat, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is P32038.
TMPY-01712	C1QB Protein, Human, Recombinant (His) complement component 1, q subcomponent, B chain,C1QB	Human	Baculovirus Insect Cells
	Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Southern blot analysis of chromosomal DNA from vertebrate species demonstrated highest similarity between the C1qB genes, followed by C1qC and finally C1qA. Sequence comparison of C1...
TMPJ-01064	Serpin G1 Protein, Mouse, Recombinant (His) Serping1,Plasma protease C1 inhibitor,C1 Inh,C1 esterase inh...	Mouse	HEK293 Cells
	SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later...
TMPJ-00980	Complement Factor MASP3 Protein, Human, Recombinant (His) PRSS5,CRARF,Serine Protease 5,MASP1,MASP-1,Mannose-Binding L...	Human	HEK293 Cells
	MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of microorganisms. Activation of the complement pathway via MBL is initiated by specific MASPs. Three MASPs have been identified and all have domain structures similar to those of C1r and C1s with a heavy chain (chain A) and a light chain (chain B). Chain A is composed of CUB1, EGF, CUB2...
TMPY-01692	NETO1 Protein, Human, Recombinant (His) neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1	Human	HEK293 Cells
	Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr...

重组蛋白

C1s Protein, Human, Recombinant (His)

Cat.No: TMPY-06585

Species: Human

Expression System: HEK293 Cells

C1s-A subcomponent Protein, Mouse, Recombinant (His)

Cat.No: TMPY-00359

Species: Mouse

Expression System: HEK293 Cells

C1SB Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02603

Species: Mouse

Expression System: E. coli

BLOC1S2 Protein, Human, Recombinant

Cat.No: TMPK-01051

Species: Human

Expression System: E. coli

BLOC1S2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02980

Species: Human

Expression System: E. coli

C1QA Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02596

Species: Mouse

Expression System: E. coli

C1QA Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02597

Species: Mouse

Expression System: P. pastoris (Yeast)

ATP6V1F Protein, Human, Recombinant (GST)

Cat.No: TMPY-04137

Species: Human

Expression System: E. coli

C1RA Protein, Mouse, Recombinant (His & Myc)

Cat.No: TMPH-02602

Species: Mouse

Expression System: E. coli

Complement factor D Protein, Rat, Recombinant (His)

Cat.No: TMPH-03272

Species: Rat

Expression System: P. pastoris (Yeast)

Complement factor D Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03271

Species: Rat

Expression System: HEK293 Cells

C1QB Protein, Human, Recombinant (His)

Cat.No: TMPY-01712

Species: Human

Expression System: Baculovirus Insect Cells

Serpin G1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01064

Species: Mouse

Expression System: HEK293 Cells

Complement Factor MASP3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00980

Species: Human

Expression System: HEK293 Cells

NETO1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01692

Species: Human

Expression System: HEK293 Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼