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Cat. No. | Product Name | Target | Signaling Pathways |
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T78105 |
PAC1R antagonist 1
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PACAP | GPCR/G Protein |
PAC1R antagonist 1为一种具有口服活性的 PAC1 受体拮抗剂,可抑制由垂体腺苷酸环化酶激活多肽(PACAP)及神经损伤所诱导的异常性疼痛,可用于研究肿瘤和与免疫相关的疾病。 | |||
T76670 |
hMC1R agonist 1
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hMC1R agonist 1 是一种有效的选择性hMC1R 激动剂(EC50=3 nM),hMC1R agonist 1 对hMC1R 的选择性是hMC3R(b>EC50=902 nM),hMC4R(b>EC50=915 nM),和hMC5R(b>EC50=>1000 nM) 的 300 倍。hMC1R agonist 1 有研究和预防黑皮质素家族疾病的潜能。 |
Cat. No. | Product Name | Species | Expression System |
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TMPH-02601 |
C1RL Protein, Mouse, Recombinant (His)
C1r-LP,C1rl,C1rlp,C1r-li... |
Mouse | E. coli |
Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum. C1RL Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.5 kDa and the accession number is Q3UZ09. | |||
TMPH-02602 |
C1RA Protein, Mouse, Recombinant (His & Myc)
Complement component 1 subcomponent r-A,C1ra,C1... |
Mouse | E. coli |
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. | |||
TMPH-02603 |
C1SB Protein, Mouse, Recombinant (His & Myc)
C1sb,C1s,Gm5077,Complement C1s-1 subcomponent,Complement com... |
Mouse | E. coli |
C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4. | |||
TMPH-02596 |
C1QA Protein, Mouse, Recombinant (E. coli, His)
C1QA,Complement C1q subcomponent subunit A |
Mouse | E. coli |
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | |||
TMPH-02597 |
C1QA Protein, Mouse, Recombinant (His)
Complement C1q subcomponent subunit A,C1QA |
Mouse | P. pastoris (Yeast) |
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. | |||
TMPY-06585 |
C1s Protein, Human, Recombinant (His)
complement component 1, s subcomponent,C1s,FLJ44757 |
Human | HEK293 Cells |
Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses. The classical complement pathway is triggered by C1, a complex composed of the binding protein C1q and two proenzymes, C1r and C1s. Upon binding of IgG to the head of C1q, C1r undergoes autoactivation and in turn cleaves and activates C1s. C1r and C1s, the proteases responsible for activation and proteolytic activity of the C1 complex of complem... | |||
TMPY-01712 |
C1QB Protein, Human, Recombinant (His)
complement component 1, q subcomponent, B chain,C1QB |
Human | Baculovirus Insect Cells |
Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Southern blot analysis of chromosomal DNA from vertebrate species demonstrated highest similarity between the C1qB genes, followed by C1qC and finally C1qA. Sequence comparison of C1... | |||
TMPJ-01064 |
Serpin G1 Protein, Mouse, Recombinant (His)
Serping1,Plasma protease C1 inhibitor,C1 Inh,C1 esterase inh... |
Mouse | HEK293 Cells |
SERPIN G1 is a member of the serpin family, The C-terminal serpin domain is similar to other serpins, and this part of C1-INH provides the inhibitory activity. SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation. SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation, blood coagulation, fibrinolysis and the generation of kinins. SERPIN G1 prevents the proteolytic cleavage of later... | |||
TMPY-01692 |
NETO1 Protein, Human, Recombinant (His)
neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1 |
Human | HEK293 Cells |
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr... | |||
TMPJ-00980 |
Complement Factor MASP3 Protein, Human, Recombinant (His)
PRSS5,CRARF,Serine Protease 5,MASP1,MASP-1,Mannose-Binding L... |
Human | HEK293 Cells |
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of microorganisms. Activation of the complement pathway via MBL is initiated by specific MASPs. Three MASPs have been identified and all have domain structures similar to those of C1r and C1s with a heavy chain (chain A) and a light chain (chain B). Chain A is composed of CUB1, EGF, CUB2... |