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Cat. No. Product Name Target Signaling Pathways
T63220 Bromodomain inhibitor-9

Others Others
Bromodomain inhibitor-9Bromodomains 抑制剂,可选择性抑制 BRD4-1的活性,其 Kd 值为 12 nM。Bromodomain inhibitor-9 能够用于与全身或脂质代谢、组织炎症、纤维化或慢性自身免疫性疾病相关疾病的研究。
T6859 I-BRD9

GSK602

Epigenetic Reader Domain Chromatin/Epigenetic
I-BRD9 (GSK602) 是一种选择性的 BRD9 细胞抑制剂,pIC50 为 7.3。
T22345 INCB054329

INCB-054329,INCB-54329,INCB-54329

Epigenetic Reader Domain Chromatin/Epigenetic
INCB054329 是一种结构不同的溴结构域和末端外结构域 (BET) 抑制剂,可抑制 BRD2-BD1、BRD2-BD2、BRD3-BD1、BRD3-BD2、BRD4-BD1、BRD4-BD2、BRDT-BD1 和 BRDT-BD2,IC50 值为 分别为 44 nM、5 nM、9 nM、1 nM、28 nM、3 nM、119 nM 和 63 nM。
T27082 CREBBP-IN-9

CREBBPIN9,CREBBP IN 9

Others Others
CREBBP-IN-9, a CREBBP inhibitor, acts on the bromodomain of the protein.
T75135 FHD-609

Others Others
FHD-609 为含溴结构域蛋白BRD9的抑制剂及降解剂,针对ncBAF,适用于研究含BAF复合亚基突变的多种癌症。FHD-609与Telomelysin或INO5401联用,或对肾上腺皮质癌(ACC)的研究具有潜在作用。
T38381 CAY17c

Others Others
CAY17c is an inhibitor of bromodomain-containing protein 4 (BRD4; IC50= 0.71 μM), as well as class I histone deacetylases (HDACs; IC50s = 0.046, 0.058, 0.075, and 0.167 μM for HDAC1, -2, -3, and -8, respectively) and class IIb HDACs (IC50s = 0.073 and 0.923 μM for HDAC6 and HDAC10, respectively).1It is selective for these enzymes over BRD2, -3, and -T (IC50s = >20 μM for all), as well as over HDAC4, -5, -7, -9, and -11 (IC50s = >10 μM for all). CAY17c inhibits the proliferation of HCT116, SW620,...

化合物

Bromodomain inhibitor-9
Cat.No: T63220
Synonym:
Target: Others
I-BRD9
Cat.No: T6859
Synonym: GSK602
Target: Epigenetic Reader Domain
INCB054329
Cat.No: T22345
Synonym: INCB-054329,INCB-54329,INCB-54329
Target: Epigenetic Reader Domain
CREBBP-IN-9
Cat.No: T27082
Synonym: CREBBPIN9,CREBBP IN 9
Target: Others
FHD-609
Cat.No: T75135
Synonym:
Target: Others
CAY17c
Cat.No: T38381
Synonym:
Target: Others
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