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Search Results for " bimatoprost acid "

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抑制剂 & 化合物

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天然产物

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Cat. No. Product Name Target Signaling Pathways
T37943 17-phenyl trinor Prostaglandin F2α isopropyl ester

17-phenyl trinor Prostaglandin F2α isopropyl ester

17-phenyl trinor PGF2α N-ethyl amide is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug, sold under the Allergan trade name Bimatoprost. The N-ethyl amide prostaglandin prodrugs are converted to the active free acid more slowly than the analogous prostaglandin ester prodrugs such as latanoprost. This product is the isopropyl ester of the free acid prostaglandin which corresponds to Bimatoprost. The free acid, 17-phenyl trinor PGF2α, is a potent FP r...
T37945 Bimatoprost methyl ester

17-phenyl trinor Prostaglandin F2α methyl ester

Prostaglandin F2α (PGF2α) drives luteolysis and smooth muscle contraction by activating the FP receptor. Bimatoprost methyl ester is a lipophilic analog of 17-phenyl trinor PGF2α, a potent agonist for the FP receptor. 17-phenyl trinor PGF2α binds the FP receptor on ovine luteal cells with a relative potency of 756% compared to that of PGF2α. Esters of PGs serve as prodrugs, as they are efficiently hydrolyzed in certain tissues to generate the bioactive free acid.

化合物

17-phenyl trinor Prostaglandin F2α isopropyl ester
Cat.No: T37943
Synonym: 17-phenyl trinor Prostaglandin F2α isopropyl ester
Target:
Bimatoprost methyl ester
Cat.No: T37945
Synonym: 17-phenyl trinor Prostaglandin F2α methyl ester
Target:
Cat. No. Product Name Target Signaling Pathways
T20939 Bimatoprost acid

17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α

GPR Endocrinology/Hormones; GPCR/G Protein
Bimatoprost acid (17-phenyl trinor PGF2α) 是一种代谢稳定的 PGF2α 类似物,对 FP 受体具有潜在的拮抗活性。与 PGF2α 相比,它与绵羊黄体细胞上的 FP 受体结合的相对效力为 756%。

天然产物

Bimatoprost acid
Cat.No: T20939
Synonym: 17-phenyl trinor PGF2α,17-phenyl trinor Prostaglandin F2α
Target: GPR
TargetMol Loading
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