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Cat. No. Product Name Target Signaling Pathways
T6011 Batimastat

巴马司他,BB94

MMP Proteases/Proteasome
Batimastat (BB94) 是广谱MMP 抑制剂,能够抑制MMP-1 (IC50:3 nM),MMP-2 (IC50:4 nM),MMP-9 (IC50:4 nM),MMP-7 (IC50:6 nM) 和 MMP-3 (IC50:20 nM)。
T10461 Batimastat sodium salt

BB-94 sodium salt

MMP Proteases/Proteasome
Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3).
T70344 BJ-2302

BJ-2302 is a SRC inhibitor. BJ-2302 effectively suppressed MDA-MB-231 cell invasion (Matrigel invasion assay) and metastasis (chorioallantoic membrane assay xenografted with MDA-MB-231-luc2-tdTomato cancer cells). Additionally, BJ-2302 (1 mg/kg) strongly suppressed TNBC cell proliferation in vitro and tumor growth in a xenograft mouse tumor model. The anti-metastatic and anti-tumor effects of BJ-2302 were superior to those of Z-FL-COCHO (1 mg/kg) or batimastat (30 mg/kg), a pan-MMP inhibitor.

化合物

Batimastat
Cat.No: T6011
Synonym: 巴马司他,BB94
Target: MMP
Batimastat sodium salt
Cat.No: T10461
Synonym: BB-94 sodium salt
Target: MMP
BJ-2302
Cat.No: T70344
Synonym:
Target:
TargetMol Loading
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