搜索结果

Search Results for " baclofen "

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T1065	Baclofen 巴氯芬,Lioresal	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Baclofen (Lioresal) 是 γ-氨基丁酸 (GABA) 的亲脂性衍生物，是可口服的选择性代谢型 GABA-B 受体激动剂，具有高血脑屏障渗透率，用于治疗因脊髓损伤和多发性硬化引起的痉挛。
T8630	Baclofen hydrochloride 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) 是一种 GAMMA-AMINOBUTYRIC ACID 衍生物，是一种特异性 GABA-B 受体激动剂。它用于治疗肌肉痉挛，尤其是由于脊髓损伤引起的肌肉痉挛。其治疗效果来自于脊髓和脊髓上部位的作用，通常是减少兴奋性传递。
T6355	(R)-baclofen STX209,Arbaclofen,(R)-巴氯芬	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	(R)-baclofen (STX209) 是一种选择性GABAB 受体激动剂。
T20962	(S)-Baclofen (+)-Baclofen,(L)-Baclofen
	(S)-Baclofen has effects on excitation in the ascending auditory pathway leading to it a potential reagent for the treatment of hyperactive auditory disorders such as hyperacusis and tinnitus.
T17306	(R)-Baclofen hydrochloride Arbaclofen hydrochloride,(R)-巴氯芬盐酸盐	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to spinal cord damage. It acts at spinal and supraspinal sites, generally reduces excitatory tra
T30118	Arbaclofen placarbil XP 19986,XP19986,XP-19986
	Arbaclofen placarbil( XP19986) is a GABA(B) receptor agonist.Arbaclofen Placarbil is a novel R-baclofen prodrug with improved absorption, distribution, metabolism, and elimination properties compared to R-baclofen. And it can reduce postprandial reflux in
T71911	CGP-11130 HCl
	4-Fluorophenibut (developmental code name CGP-11130; also known as β-(4-fluorophenyl)-γ-aminobutyric acid or β-(4-fluorophenyl)-GABA) is a GABAB receptor agonist which was never marketed. It is selective for the GABAB receptor over the GABAA receptor (IC50 = 1.70 μM and > 100 μM, respectively). The drug is a GABA analogue and is closely related to baclofen (β-(4-chlorophenyl)-GABA), tolibut (β-(4-methylphenyl)-GABA), and phenibut (β-phenyl-GABA). It is less potent as a GABAB receptor agonist t...
T38192	Unifiram	Others	Others
	Unifiram 是一种认知增强剂。 Unifiram 诱导大鼠海马 CA1 区场兴奋性突触后电位 (fEPSP) 幅度的持久增加 (EC50= 27 nM) 并增加大鼠大脑皮层中乙酰胆碱 (ACh) 的释放。