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Cat. No. Product Name Target Signaling Pathways
T70040 BRD5814

BRD5814 is a highly brain penetrant β-arrestin biased D2R antagonist.
T70039 BIM-46174

BIM-46174 is a New Inhibitor of the Heterotrimeric Gα/Gβγ Protein Complex. BIM-46174 acts as a selective inhibitor of heterotrimeric G-protein complex. BIM-46174 prevents the heterotrimeric G-protein signaling linked to several GPCRs mediating (a) cyclic AMP generation (Gαs), (b) calcium release (Gαq), and (c) cancer cell invasion by Wnt-2 frizzled receptors and high-affinity neurotensin receptors (Gαo/i and Gαq). BIM-46174 inhibits the growth of a large panel of human cancer cell lines, includ...

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BRD5814
Cat.No: T70040
Synonym:
Target:
BIM-46174
Cat.No: T70039
Synonym:
Target:
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