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Search Results for " bpk "

Targets Recommended: Others

5

抑制剂 & 化合物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13586L	BPK-29 hydrochloride	Others	Others
	BPK-29 hydrochloride 是特殊配体，能够共价修饰 C274 ，破坏非典型孤核受体NR0B1与RBM45、SNW1蛋白质的相互作用。它能够损害KEAP1突变癌细胞的锚定独立生长。
T39829	BPK-25
	BPK-25 is an active acrylamide compound that enhances the degradation of proteins in the nucleosome remodeling and deacetylation (NuRD) complex through a post-translational mechanism involving covalent protein interaction. Additionally, BPK-25 acts as an inhibitor of TMEM173 activation by the cyclic dinucleotide ligand cGAMP.
T39828	BPK-21
	BPK-21 is an active acrylamide compound that effectively suppresses T cell activation by blocking the function of ERCC3, a helicase enzyme. BPK-21 specifically targets C342 within the ERCC3 helicase.
T13586	BPK-29	Others	Others
	BPK-29 is a specific ligand that disrupts the atypical orphan nuclear receptor NR0B1-protein interactions by covalently modifying C274. It impairs the anchorage-independent growth of KEAP1-mutant cancer cells.
T25172	BPKDi
	BPKDi is a potent and selective inhibitor of PKD (protein kinase D).

化合物

BPK-29 hydrochloride

Cat.No: T13586L

Target: Others

Cat.No: T39829

Cat.No: T39828

Cat.No: T13586

Target: Others

Cat.No: T25172

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02271	BTK Protein, Human, Recombinant (His) BPK,AGMX1,ATK,B-cell progenitor kinase,Tyrosine-pro...	Human	Baculovirus Insect Cells
	Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...

重组蛋白

BTK Protein, Human, Recombinant (His)

Cat.No: TMPH-02271

Species: Human

Expression System: Baculovirus Insect Cells

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