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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0787 |
Butylhydroxyanisole
BHA,丁基羟基茴香醚,丁基大茴香醚,E320,Butylated hydroxyanisole |
Antioxidant; Ferroptosis; Reactive Oxygen Species | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction |
Butylhydroxyanisole (BHA) 是一种抗氧化剂,能介导肝毒性、生殖器官发育和学习迟缓以及睡眠不足,用作食品防腐剂。它也是一种铁死亡诱导剂,能导致大脑和神经发育中断,具有神经毒性。 | |||
T21719 |
CBHA
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m-Carboxycinnamic acid bishydroxamide 是一种有效的HDAC 抑制剂,在体外对 HDAC1 和 HDAC3 的ID50值分别为 10 nM 和 70 nM。m-Carboxycinnamic acid bishydroxamide 也可诱导细胞凋亡并且抑制肿瘤生长。 | |||
T26790 |
Bharangin
|
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Bharangin is a inhibitor of penicillinase enzyme in E coli. | |||
T34974 |
U 104489
U104489,PNU-104489,PNU 104489,PNU104489,U-104489 |
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U 104489 (PNU-104489) is a novel specific inhibitor of human immunodeficiency virus 1 (HIV-1), showing effective activity against BHA-P-resistant HIV-1MF. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN6750 |
2-tert-Butyl-1,4-benzoquinone
|
Nrf2 | Immunology/Inflammation |
2-tert-Butyl-1,4-benzoquinone 是丁基化羟基茴香醚 (BHA) 的亲电子代谢物,它在 RAW264.7 细胞中引起 Nrf2 的活化及其负调节剂 Keap1 的 S-芳基化。 | |||
TN4650 |
Nervogenic acid
|
Antifection | Microbiology/Virology |
Nervogenic acid has antioxidative, pro-coagulant, and antibacterial activities, it exhibits higher activity than that of t-butyl-4- hydroxyanisole (BHA) using the ferric thiocyanate method. | |||
TN5189 |
Tristin
|
Others | Others |
Tristin shows stronger antioxidative activity than butylated hydroxyanisole (BHA). |