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4

抑制剂 & 化合物

3

天然产物

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Cat. No. Product Name Target Signaling Pathways
T0787 Butylhydroxyanisole

BHA,丁基羟基茴香醚,丁基大茴香醚,E320,Butylated hydroxyanisole

Antioxidant; Ferroptosis; Reactive Oxygen Species Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; oxidation-reduction
Butylhydroxyanisole (BHA) 是一种抗氧化剂,能介导肝毒性、生殖器官发育和学习迟缓以及睡眠不足,用作食品防腐剂。它也是一种铁死亡诱导剂,能导致大脑和神经发育中断,具有神经毒性。
T21719 CBHA

m-Carboxycinnamic acid bishydroxamide 是一种有效的HDAC 抑制剂,在体外对 HDAC1 和 HDAC3 的ID50值分别为 10 nM 和 70 nM。m-Carboxycinnamic acid bishydroxamide 也可诱导细胞凋亡并且抑制肿瘤生长。
T26790 Bharangin

Bharangin is a inhibitor of penicillinase enzyme in E coli.
T34974 U 104489

U104489,PNU-104489,PNU 104489,PNU104489,U-104489

U 104489 (PNU-104489) is a novel specific inhibitor of human immunodeficiency virus 1 (HIV-1), showing effective activity against BHA-P-resistant HIV-1MF.

化合物

Butylhydroxyanisole
Cat.No: T0787
Synonym: BHA,丁基羟基茴香醚,丁基大茴香醚,E320,Butylated hydroxyanisole
Target: Antioxidant, Ferroptosis, Reactive Oxygen Species
CBHA
Cat.No: T21719
Synonym:
Target:
Bharangin
Cat.No: T26790
Synonym:
Target:
U 104489
Cat.No: T34974
Synonym: U104489,PNU-104489,PNU 104489,PNU104489,U-104489
Target:
Cat. No. Product Name Target Signaling Pathways
TN6750 2-tert-Butyl-1,4-benzoquinone

Nrf2 Immunology/Inflammation
2-tert-Butyl-1,4-benzoquinone 是丁基化羟基茴香醚 (BHA) 的亲电子代谢物,它在 RAW264.7 细胞中引起 Nrf2 的活化及其负调节剂 Keap1 的 S-芳基化。
TN4650 Nervogenic acid

Antifection Microbiology/Virology
Nervogenic acid has antioxidative, pro-coagulant, and antibacterial activities, it exhibits higher activity than that of t-butyl-4- hydroxyanisole (BHA) using the ferric thiocyanate method.
TN5189 Tristin

Others Others
Tristin shows stronger antioxidative activity than butylated hydroxyanisole (BHA).

天然产物

2-tert-Butyl-1,4-benzoquinone
Cat.No: TN6750
Synonym:
Target: Nrf2
Nervogenic acid
Cat.No: TN4650
Synonym:
Target: Antifection
Tristin
Cat.No: TN5189
Synonym:
Target: Others
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