Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T36198 |
Avenanthramide-C methyl ester
|
||
Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC50 ~ 40 μM). Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells. |