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Search Results for " autophagy-targeting chimeras "

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Cat. No.	Product Name	Target	Signaling Pathways
T60015	TSPO ligand-2 Carbonic acid	AUTACs	PROTAC
	TSPO ligand-2 (Carbonic acid) 是 AUTAC1 的配体，AUTAC1含有一个对氟苄基鸟嘌呤和一个烟曲霉醇部分。
T82632	Cys-C-cGMP	AUTACs	PROTAC
	Cys-C-cGMP 为一种AUTACs自噬标签。它能够促进HeLa细胞线粒体K63链式连接的泛素化增加。
T11701	J22352	Caspase	Apoptosis; Proteases/Proteasome
	J22352, a PROTAC (proteolysis-targeting chimeras)-like and highly selective HDAC6 inhibitor with an IC50 value of 4.7 nM, enhances anticancer effects in glioblastoma by promoting HDAC6 degradation. It does so by inhibiting autophagy and stimulating the antitumor immune response, further restoring host antitumor activity through the reduction of PD-L1's immunosuppressive activity.