Cat. No. | Product Name | Target | Signaling Pathways |
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T6767 |
TCS7010
Aurora A Inhibitor I |
Apoptosis; Aurora Kinase | Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic |
TCS7010 (Aurora A Inhibitor I) 是一种选择性的 Aurora A 抑制剂,IC50值为 3.4 nM。 | |||
T35459 |
Glycyl H-1152 hydrochloride
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Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. Glycyl-H-1152 is a selective and potent ROCK inhibitor (IC50 = 11.8 nM for ROCK-II). It is a glycylated isoquinoline compound derived from the therapeutically-important ROCK inhibitor HA-1077 (Fasudil) and exhibits bett... |