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Cat. No. Product Name Target Signaling Pathways
T14312 Apratastat

MMP; TNF Apoptosis; Proteases/Proteasome
Apratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) and it also can potently inhibit the release of TNF-α in vitro, ex vivo, and in vivo with IC50s of 144 ng/mL in vitro and 81.7 ng/mL ex vivo, respectively[1].

化合物

Apratastat
Cat.No: T14312
Synonym:
Target: MMP, TNF
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