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Search Results for " apoe4 "

Targets Recommended: Others

3

抑制剂 & 化合物

4

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T16518	PH-002	Others	Others
	PH-002 是一种抑制载脂蛋白 E4 神经内分子相互作用的抑制剂(IC50:116 nM)。
T15265	EZ-482	Others	Others
	EZ-482 is a novel ligand of apolipoprotein (apoE). EZ-482 binds to apoE4 by a unique N-terminal allosteric effect and it also binds to sites on apoE in the C-terminal domain (Kds: 5-10 μM for apoE3 and apoE4).
T36521	Alaproclate (hydrochloride)
	Alaproclate is a selective serotonin reuptake inhibitor (SSRI).1,2 It inhibits depletion of serotonin (5-HT) induced by 4-methyl-α-ethyl-m-tyramine in rat cerebral cortex, hippocampus, hypothalamus, and striatum (EC50s = 18, 4, 8, and 12 mg/kg, respectively).1 Alaproclate inhibits NMDA-evoked currents and depolarization-induced voltage-dependent potassium currents in rat hippocampal neurons (IC50s = 1.1 and 6.9 μM, respectively) and does not inhibit GABA-evoked currents when used at concentratio...

化合物

Cat.No: T16518

Target: Others

Cat.No: T15265

Target: Others

Alaproclate (hydrochloride)

Cat.No: T36521

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-00588	Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) Apolipoprotein E,Apo-E,apolipo E,APOE4,	Human	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells w...
TMPK-00589	Apolipoprotein E/APOE4 Protein, Human, Recombinant (His) APOE,apolipo E,Apo-E,APOE4,Apolip...	Human	HEK293 Cells
	Apolipoprotein E (apoE) is a lipid carrier in both the peripheral and the central nervous systems. Lipid-loaded apoE lipoprotein particles bind to several cell surface receptors to support membrane homeostasis and injury repair in the brain. Considering prevalence and relative risk magnitude, the ε4 allele of the APOE gene is the strongest genetic risk factor for late-onset Alzheimer's disease (AD). Apolipoprotein E/APOE4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) LPG,apolipoprotein E,ApoE4,APO-E,LDLCQ5,AD...	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated APO-E,LDLCQ5,LPG,ApoE4,AD2,apolipoprotein ...	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.

重组蛋白

Apolipoprotein E/APOE4 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00588

Species: Human

Expression System: HEK293 Cells

Apolipoprotein E/APOE4 Protein, Human, Recombinant (His)

Cat.No: TMPK-00589

Species: Human

Expression System: HEK293 Cells

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)

Cat.No: TMPY-05297

Species: Human

Expression System: E. coli

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated

Cat.No: TMPY-05528

Species: Human

Expression System: E. coli

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