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Cat. No. Product Name Target Signaling Pathways
T22119 NS3694

Apoptosis Apoptosis
NS3694 是一种凋亡抑制剂,可抑制凋亡小体形成和半胱天冬酶活化。
T1772 MDK83190

Apoptosis Activator 2

Apoptosis; Caspase Apoptosis; Proteases/Proteasome
MDK83190 (Apoptosis Activator 2) 是一种细胞凋亡激活剂,可诱导 caspase-3 激活、Apaf-1 寡聚化、PARP 切割和 DNA 片段化。
T12599 QM31

SVT016426

Others Others
QM31 is a selective Apaf-1 inhibitor(inbitita formation of the apoptosome with IC50 of 7.9μM).
T13417 ZYZ-488

Others Others
ZYZ-488 is a competitive inhibitor of apoptotic protease activating factor-1 (Apaf-1).
TP2237 Cytochrome c fragment (93-108)

Others Others
Cytochrome c fragment (93-108) is a peptide from Cytochrome c, which is a small heme protein found loosely associated with the inner membrane of the mitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1. Cytochrome c is a required cofactor for Apaf-1 function2.
TP2238 Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]

Others Others
Cytochrome P450 CYP1B1 (190-198) [Homo sapiens] is a peptide from Cytochrome c, which is a small heme protein found loosely associated with the inner membrane of the mitochondrion. Cytochromes c from certain eukaryotes, including plants and fungi but not higher animals, contains methylated lysine residues at specific positions1. Cytochrome c is a required cofactor for Apaf-1 function2.
T36190 CAY10443

CAY10443

Mitochondrial release of cytochrome c triggers apoptosis via the assembly of a multimeric complex including caspase-9, Apaf-1, and other components, sometimes called the apoptosome. Library screens have identified small molecules that activate the apoptosome by binding to one or more of its components. CAY10443 is one such molecule. In a cell free, multi-component assay, it activated caspase-3 with an EC50 of 5 μM. These apoptotic activators represent therapeutic lead compounds for the developme...

化合物

NS3694
Cat.No: T22119
Synonym:
Target: Apoptosis
MDK83190
Cat.No: T1772
Synonym: Apoptosis Activator 2
Target: Apoptosis, Caspase
QM31
Cat.No: T12599
Synonym: SVT016426
Target: Others
ZYZ-488
Cat.No: T13417
Synonym:
Target: Others
Cytochrome c fragment (93-108)
Cat.No: TP2237
Synonym:
Target: Others
Cytochrome P450 CYP1B1 (190-198) [Homo sapiens]
Cat.No: TP2238
Synonym:
Target: Others
CAY10443
Cat.No: T36190
Synonym: CAY10443
Target:
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