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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T62967 | Anti-inflammatory agent 10 | ||
Anti-inflammatory agent 10 是一种基于 tilomisole 的苯并咪唑噻唑衍生物,口服具有活性。Anti-inflammatory agent 10 对 COX-2 酶的活性比 COX-1 高。 | |||
T38240 |
2,6-Dichlorodiphenylamine
|
Antibacterial | Microbiology/Virology |
2,6-Dichlorodiphenylamine 是双氯芬酸钠的一种结构类似物,显示出抗白色念珠菌活性。2,6-Dichlorodiphenylamine 是非选择性抗炎剂,为COX 的抑制剂,在 CHO 细胞中,对人 COX-1 和 COX-2 的IC50分别为 4 和 1.3 nM。 | |||
T61149 | Antibacterial agent 121 | ||
Antibacterial agent 121 (Compound 10) demonstrates antibacterial properties and exhibits efficacy against mycobacterial strains while also possessing anti-inflammatory activity. This compound finds potential applications in Tuberculosis (TB) research [1]. | |||
T79473 | Anti-inflammatory agent 46 | NO Synthase | Immunology/Inflammation |
Anti-inflammatory agent 46(compound 7h)是一种能够抑制一氧化氮(NO)生成的化合物,通过与iNOS低能量结合,在体内有效减缓小鼠肿胀(剂量为10 mg/kg)。 | |||
T35708 | N-acetyl-5-Aminosalicylic Acid | ||
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine . It is formed in the liver, intestinal lumen, and colonic epithelial cells via N-acetyltransferases. It reduces IFN-γ binding to colonic epithelial cells by 24% when used at a concentration of 10 mM. N-acetyl-5-Aminosalicylic acid (100 μM) scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay and inhibits base hydroxylation in DNA stimulated by ... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1168 |
Desonide
Tridesilon,地索奈德,Locapred,Prednacinolone |
Glucocorticoid Receptor | Endocrinology/Hormones |
Desonide (Prednacinolone) 是一种非氟化皮质类固醇抗炎剂,能够作用于糖皮质激素受体。 |