3
2
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7814 |
Alloxan monohydrate
|
Proteasome | Proteases/Proteasome; Ubiquitination |
Alloxan Monohydrate 是一种能够引起糖尿病的致糖尿病药物。它作为蛋白酶体抑制剂,破坏胰腺中能够分泌胰岛素的B 细胞,导致实验动物患糖尿病。 | |||
T8391 |
Cesium chloride
氯化铯,CsCl |
Potassium Channel | Membrane transporter/Ion channel |
Cesium chloride (CsCl) 是一种钾通道抑制剂,可以防止 Alloxan 引起的 Na+转运减少。Cesium chloride 可以诱发心律失常。 | |||
T27324 |
FK614
FK 614,ATx-08-001,ATx-08001,FK-614 |
||
FK-614 is a selective agonist of peroxisome proliferator-activated receptor gamma. FK-614 improves peripheral glucose utilization while decreases hepatic insulin extraction in alloxan-induced diabetic dogs. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7814L |
Alloxan
NSC 7169,NSC7169,NSC-7169 |
||
Alloxan is an acidic compound formed by the oxidation of URIC ACID. | |||
TN3532 | Borapetoside E | Others | Others |
Borapetoside E has anti-hyperglycemic activity, it can significantly reduce serum glucose levels at dose-dependent manners in alloxan-induced hyperglycemic mice and db/db type 2 diabetic mice. |