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Cat. No. Product Name Target Signaling Pathways
T70741 AZ-TAK1

AZ-Tak1 is a potent and a relatively selective inhibitor of TAK1 kinase activity, with an IC50 of 0.009 mM. AZ-Tak1 treatment decreased the level of p38 and ERK in mantle cell lymphoma cells, and induced apoptosis in a dose and time dependent manner, with an IC50 of 0.1–0.5 mM. Using the annexin-V and PI staining and FACS analysis, After 48 hours of incubation, AZ-Tak1 (0.1 mM) induced apoptosis in 28%, 34% and 86% of Mino, SP53, and Jeko cells, respectively, which was increased to 32%, 42%, and...
T70739 KW 4099

KW 4099 is a thromboxane A2 antagonist.

化合物

AZ-TAK1
Cat.No: T70741
Synonym:
Target:
KW 4099
Cat.No: T70739
Synonym:
Target:
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