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Targets Recommended: PDE

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T30232	AWD 12-281 GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470	PDE	Metabolism
	AWD 12-281 是一种选择性磷酸二酯酶 4 (PDE4) 抑制剂，具有抗炎活性和支气管扩张活性，用于研究慢性阻塞性肺疾病（COPD）。
T30233	AWD-G256
	AWD-G256 是一种抗心律失常物质，AWD-G256 对卒中量、肺压和全身血压没有显著影响。
T1860	Imepitoin AWD 131-138,ELB-138,伊匹妥英	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Imepitoin (AWD 131-138) 是一种新型的低亲和力部分苯二氮卓受体激动剂，有抗惊厥和抗焦虑作用。
T34387	Ronomilast AWD 12353,ELB-353,Elbimilast,ELB353,ELB 353	Others	Others
	Ronomilast (ELB353) 可用于研究阻塞性肺疾。
T26694	AWD12−281 AWD 12281,AWD12281,AWD 12−281,AWD-12−281,AWD-12281
	AWD12−281 is an inhibitor of PDE4.
T26279	Tiracizine HCl AWD-19-166,AWD19166,Bonnecor,AWD 19 166,Tiracizine Hydrochloride
	Tiracizine HCl 是一种新的I 类抗心律失常药物，对缺血性心脏病患者进行了研究，结果表明该药物可降低心肌收缩功能。
T68188	AWD 26-06
	AWD 26-06 is a muscarinic-1-antagonist.
T71473	AWD 122-60
	AWD 122-60 is a cardiotonic bipyridine that inhibits adenosine triphosphate-sensitive potassium channels of mouse skeletal muscle.
T69614	Ethybenztropine HBr
	Ethybenztropine HBr is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor.
T69615	AWD12-281 sodium
	AWD 12-281 is a selective phosphodiesterase 4 (PDE4) inhibitor for the treatment of lung inflammation using inhalative administration. AWD 12-281 Is Active in a New Guinea-Pig Model of Allergic Skin Inflammation Predictive of Human Skin Penetration and Suppresses Both Th1 and Th2 Cytokines in Mice. AWD 12-281 is a very promising drug candidate not only for the treatment of lung inflammation using inhalative administration but also for the treatment of atopic dermatitis.

化合物

AWD 12-281

Cat.No: T30232

Synonym: GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470

Synonym: AWD 131-138,ELB-138,伊匹妥英

Target: GABA Receptor

Ronomilast

Cat.No: T34387

Synonym: AWD 12353,ELB-353,Elbimilast,ELB353,ELB 353

Target: Others

AWD12−281

Cat.No: T26694

Synonym: AWD 12281,AWD12281,AWD 12−281,AWD-12−281,AWD-12281

Target:

Tiracizine HCl

Cat.No: T26279

Synonym: AWD-19-166,AWD19166,Bonnecor,AWD 19 166,Tiracizine Hydrochloride

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04467	NME1 Protein, Human, Recombinant (His) NME/NM23 nucleoside diphosphate kinase 1,NB,NDPK-A,NM23-H1,N...	Human	E. coli
	NME1, also known as Nucleoside Diphosphate Kinase A (NDK-A), or NM23-H1, belongs to the NDK family. NM23-H1 is known to have a metastasis suppressive activity in many tumor cells. Recent studies have shown that the interacting proteins with NM23-H1 which mediate cell proliferation, may act as modulators of the metastasis suppressor activity. The interacting proteins with NM23-H1 can be classified into 3 groups. The first group of proteins can be classified as upstream kinases of NM23-H1 such as ...