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Cat. No.	Product Name	Species	Expression System
TMPY-03268	GABARAPL1 Protein, Human, Recombinant (His) GEC1,APG8-LIKE,APG8L,ATG8	Human	E. coli
	ATG8, also known as GABARAPL1, is a ubiquitin-like protein that has a crystal structure. ATG8 consists of a 5-stranded β-sheet, which is enclosed by two α-helices at one side and one α-helix at the other side and exhibits a conserved GABARAP domain. It functions in the formation of autophagosomal membranes. The transient conjugation of ATG8 to the autophagosomal membrane through a ubiquitin-like conjugation system is essential for autophagy in eukaryotes. Autophagy is induced upon nutrient deple...
TMPY-03461	GABARAPL2 Protein, Human, Recombinant (His) GATE16,ATG8,ATG8C,GEF-2,...	Human	E. coli
	GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and small intestine. GATE-16 is involved in intra-Golgi traffic. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
TMPJ-01321	MAP1LC3B Protein, Human, Recombinant Autophagy-related ubiquitin-like modifier LC3 B,MAP1A/MAP1B ...	Human	E. coli
	Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) is a member of the highly conserved ATG8 protein family. ATG8 proteins are present in all known eukaryotic organisms. MAP1LC3B is one of the four genes in the MAP1LC3 subfamily (others include MAP1LC3A, MAP1LC3C, and MAP1LC3B2). It is moat abundantly expressed in heart, brain, skeletal muscle and testis. LMAP1LC3B is a subunit of neuronal microtubule and functions in formation of autophagosomal vacuoles (autophagosomes). It associat...
TMPH-01684	MAP1LC3C Protein, Human, Recombinant (His)	Human	E. coli
	Ubiquitin-like modifier that plays a crucial role in antibacterial autophagy (xenophagy) through the selective binding of CALCOCO2. Recruits all ATG8 family members to infecting bacteria such as S.Typhimurium. May also play a role in aggrephagy, the macroautophagic degradation of ubiquitinated and aggregated proteins. MAP1LC3C Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.7 kDa and the accession number is Q9BXW...
TMPY-00587	GABARAP Protein, Human, Recombinant (His & MBP) GABARAP-a,GABA(A) receptor-associated protein,ATG	Human	E. coli
	The Atg8/LC3/GABARAP family of proteins, a group that has structural homology with ubiquitin, connects with a large set of binding partners to function in macroautophagy (hereafter autophagy). GABARAP in tumorigenesis in vivo by delaying cell death and its associated immune-related response. GABARAPs are uniquely required for antimicrobial host defense through cytosolic distribution of interferon-inducible GTPases. GABARAPs as the first known direct interaction partners of Nef that are essential...
TMPJ-01354	ATG3 Protein, Human, Recombinant ATG3,Ubiquitin-like-conjugating enzyme ATG...	Human	E. coli
	Ubiquitin-like-conjugating enzyme ATG3 (ATG3), also known as Apg3L and Apg3p, functions as a regulatory component of autophagosome biogenesis necessary for autophagy. ATG3 exhibits 98% aa sequence identity with both its mouse and rat orthologs. It is widely expressed and has highly levels in heart, skeletal muscle, kidney, liver and placenta. As an E2-like enzyme, involves in autophagy and mitochondrial homeostasis. ATG3 catalyzes the conjugation of ATG8-like proteins to PE which is essential fo...
TMPH-02632	TRIM21 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr...
TMPH-02633	TRIM21 Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr...

重组蛋白

GABARAPL1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03268

Species: Human

Expression System: E. coli

GABARAPL2 Protein, Human, Recombinant (His)

Cat.No: TMPY-03461

Species: Human

Expression System: E. coli

MAP1LC3B Protein, Human, Recombinant

Cat.No: TMPJ-01321

Species: Human

Expression System: E. coli

MAP1LC3C Protein, Human, Recombinant (His)

Cat.No: TMPH-01684

Species: Human

Expression System: E. coli

GABARAP Protein, Human, Recombinant (His & MBP)

Cat.No: TMPY-00587

Species: Human

Expression System: E. coli

ATG3 Protein, Human, Recombinant

Cat.No: TMPJ-01354

Species: Human

Expression System: E. coli

TRIM21 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02632

Species: Mouse

Expression System: E. coli

TRIM21 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02633

Species: Mouse

Expression System: Baculovirus Insect Cells

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