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Targets Recommended: Autophagy

2

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T23716	AMDE-1 AMDE 1	Autophagy	Autophagy
	AMDE-1 是一种自噬调节剂，以 Atg5 依赖性方式触发自噬。 AMDE-1 将 Atg16 募集到自噬体前位点并导致 LC3 脂化。
T72561	Antitumor agent-82
	Antitumor agent-82是一种有效的抗肿瘤剂。Antitumor agent-82 显示出抗增殖活性。Antitumor agent-82 通过 ATG5/ATG7信号通路诱导细胞自噬 (Autophagy)。

化合物

Cat.No: T23716

Synonym: AMDE 1

Target: Autophagy

Antitumor agent-82

Cat.No: T72561

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01329	ATG5 Protein, Human, Recombinant ASP,APG5L,Apoptosis-specific protein,Autophagy prot...	Human	E. coli
	ATG5 is an E2 ubiquitin ligase which is necessary for autophagy. Its expression is a relatively late event in the apoptotic process, occurring downstream of caspase activity, dramatically highly expressed in apoptotic cells. It is activated by ATG7, conjugates to ATG12 and associates with isolation membrane to form cup-shaped isolation membrane and autophagosome. The conjugate complex detaches from the membrane immediately before or after autophagosome formation is completed. ATG5 plays an impor...
TMPJ-01327	ATG10 Protein, Human, Recombinant (His, T7) ATG10,APG10-Like,Ubiquitin-Like-Conjugating Enzyme ...	Human	E. coli
	Ubiquitin-Like-Conjugating Enzyme ATG10 (ATG10) is a ubiquitous 28kDa member of the ATG10 family protein. ATG10 acts as an E2-like enzyme, catalyzes the transfer of ATG12 to ATG5 during in the initial stages of autophagesome formation. The heterodimer of ATG5 and ATG12 subsequntly associates non-covalently with an ATG16 multimer to generate an antophagosome. ATG10 plays a role in the conjugation of ATG12 to ATG5 by interaction with MAP1LC3A. In addition, ATG10 can diretly interact with ATG5 or A...
TMPH-01287	TUFM Protein, Human, Recombinant (His)	Human	E. coli
	Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG-I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy.

重组蛋白

ATG5 Protein, Human, Recombinant

Cat.No: TMPJ-01329

Species: Human

Expression System: E. coli

ATG10 Protein, Human, Recombinant (His, T7)

Cat.No: TMPJ-01327

Species: Human

Expression System: E. coli

TUFM Protein, Human, Recombinant (His)

Cat.No: TMPH-01287

Species: Human

Expression System: E. coli

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