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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T79756 |
Beclin1-ATG14L interaction inhibitor 1
|
Autophagy | Autophagy |
Beclin1-ATG14L interaction inhibitor 1 (com 19) 作为一种选择性抑制剂,特定抑制脂质激酶VPS34的复合物 I 中Beclin1与ATG14L的相互作用,而对Beclin 1-UVRAG作用重要的VPS34复合物 II 无影响。由此,其阻断VPS34复合物 I 形成,抑制自噬过程,但不干扰复合物 II 介导的囊泡运输。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01003 |
ATG14 Protein, Human, Recombinant (His & Myc)
Barkor,Autophagy-related protein 14-like protein, |
Human | E. coli |
ATG14 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 60.3 kDa and the accession number is Q6ZNE5. | |||
TMPY-00473 |
NRBF2 Protein, Human, Recombinant (His & GST)
NRBF-2,nuclear receptor binding factor 2,COPR2,COPR1 |
Human | Baculovirus Insect Cells |
NRBF2 (Nuclear Receptor Binding Factor 2) is a Protein Coding gene. The encoded protein may modulate transcriptional activation by target nuclear receptors. It is widely expressed in the appendix, placenta, and other tissues. NRBF2/Atg38 has been identified as the fifth subunit of the macroautophagy/autophagy class III phosphatidylinositol 3-kinase (PtdIns3K) complex, along with ATG14/Barkor, BECN1/Vps30, PIK3R4/p150/Vps15, and PIK3C3/Vps34. NRBF2 is a critical molecular switch of PtdIns3K and a... |