Cat. No. | Product Name | Target | Signaling Pathways |
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T74778 | ASM-IN-1 | Phospholipase | Metabolism |
ASM-IN-1是一种高效的口服活性ASM抑制剂,具有1.5 µM的IC50值。该化合物在减少主动脉弓及主动脉的脂质斑块方面表现出效果,并能够降低血浆中的神经酰胺以及Ox-LDL水平。ASM-IN-1展现了抗动脉粥样硬化与抗炎的活性。 | |||
T37436 |
C12-Ceramide
N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine |
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C12-Ceramide (C12 Ceramide (d18:1/12:0)) 是一种存在于先兆子痫妇女所生婴儿围绕脐带血管的保护膜的神经酰胺,是 C12 鞘磷脂被酸性鞘磷脂酶(ASM)水解后形成的,可用于评估 A 型或 B 型尼曼-皮克病患者血浆中的 ASM 活性水平。 | |||
T37116 |
Ethylmalonyl Coenzyme A (sodium salt)
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Ethylmalonyl coenzyme A (CoA) is a key intermediate in the ethylmalonyl-CoA pathway for carbon metabolism in certain bacteria, such asM. extorquens, which uses this pathway when grown on ethylamine.1,2It is produced from crotonyl-CoA by crotonyl-CoA reductase/carboxylase and modified by ethylmalonyl-CoA mutase to make methylsuccinyl-CoA. 1.Good, N.M., Martinez-Gomez, N.C., Beck, D.A.C., et al.Ethylmalonyl coenzyme A mutase operates as a metabolic control point in Methylobacterium extorquens AM1J... |