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Search Results for " apex "

Targets Recommended: Others

2

抑制剂 & 化合物

1

天然产物

2

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T9423	Alkyne tyramide	Others	Others
	Alkyne tyramide 是抗坏血酸过氧化物酶 2 探针。它有助于鉴定 APEX 标记位点，明确线粒体蛋白的膜拓扑的分配。它显著提高了完整酵母细胞的 APEX 标记效率，比 APEX2 底物生物素苯酚具有更大的细胞壁渗透性。
T68656	Brivudine monophosphate
	Brivudine monophosphate is a phosphate ester of Brivudine. Brivudine, also known as bromovinyl-deoxyuridine, is a uridine derivative and nucleoside analog with pro-apoptotic and chemosensitizing properties. In vitro, bromovinyl-deoxyuridine (BVDU) has been shown to downregulate the multifunctional DNA repair enzyme APEX nuclease 1, resulting in the inhibition of DNA repair and the induction of apoptosis. In addition, this agent may inhibit the expression of STAT3 (signal transducer and activator...

化合物

Alkyne tyramide

Cat.No: T9423

Target: Others

Brivudine monophosphate

Cat.No: T68656

Cat. No.	Product Name	Target	Signaling Pathways
T82799	C-2′-Decoumaroylaloeresin G
	C-2′-Decoumaroylaloeresin G (化合物8)为一种色酮糖苷，源自芦荟属植物。

天然产物

C-2′-Decoumaroylaloeresin G

Cat.No: T82799

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02433	APE1/APEX1 Protein, Human, Recombinant (His) APEX,HAP1,APX,APE,APEX nuclease (multifunc...	Human	E. coli
	The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease, DNA 3' repair diesterase, 3'-5' exonuclease and DNA 3'-phosphatase activities.Although Apex mRNA was expressed ubiquitously, the levels varied significantly, suggesting organ- or tissue-specific expression of the Apex gene. The highest level was observed in the testis, relatively high levels in the...
TMPJ-00464	APE Protein, Human, Recombinant APEX,Apurinic-Apyrimidinic Endonuclease 1,APEN,DNA-...	Human	E. coli
	Apurinic-Apyrimidinic Endonuclease 1 (APE1) is required for efficient DNA base excision repair. When the DNA glycosylase remove the damaged bases, APE1 cleaves the AP site to allow resynthesis and ligation to complete repair. APE1 stimulates the DNA binding activity of many transcription factors, which participate in cancer promotion and progression. APE1 regulates the redox state of multiple transcription factors, such as c-Jun, c-Fos, NF-kB, p53. APEN is also involved in calcium-dependent down...

重组蛋白

APE1/APEX1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02433

Species: Human

Expression System: E. coli

APE Protein, Human, Recombinant

Cat.No: TMPJ-00464

Species: Human

Expression System: E. coli

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