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Cat. No.	Product Name	Target	Signaling Pathways
T61068	AMPA receptor antagonist-2	iGluR	Membrane transporter/Ion channel; Neuroscience
	AMPA receptor antagonist-2是一种AMPA 受体拮抗剂。
T7304	DNQX 二硝基喹酮,FG 9041	GluR; iGluR	Membrane transporter/Ion channel; Neuroscience
	DNQX (FG 9041) 是喹恶啉衍生物，是一种选择性和强竞争性的非 NMDA 谷氨酸受体拮抗剂，对 AMPA、kainate 和 NMDA 受体的IC50分别为 0.5、2 和 40 μM。
T8459	DNQX disodium salt DNQX Disodium	NMDAR; iGluR	Membrane transporter/Ion channel; Neuroscience
	DNQX disodium salt 是一种选择性、强竞争性的非 NMDA 谷氨酸受体 (non-NMDA glutamate receptor) 拮抗剂 (对 AMPA、kainate 和 NMDA 受体的 IC50分别为 0.5、2 和 40 μM)，是一种喹恶啉衍生物。
T38192	Unifiram	Others	Others
	Unifiram 是一种认知增强剂。 Unifiram 诱导大鼠海马 CA1 区场兴奋性突触后电位 (fEPSP) 幅度的持久增加 (EC50= 27 nM) 并增加大鼠大脑皮层中乙酰胆碱 (ACh) 的释放。
T21875	CP-465022 (maleate)
	CP-465022 Maleate is a potent, selective, noncompetitive AMPA receptor antagonist with anticonvulsant activity. It effectively counters the Kainate-induced response in rat cortical neurons, exhibiting an IC 50 of 25 nM. As such, CP-465022 Maleate presents a valuable instrument for studying the involvement of AMPA receptors in various physiological and pathophysiological processes [1] [2].
T28034	MGS-0039 BCI 632,BCI-632,MGS0039,BCI632
	MGS-0039 is a group II metabotropic glutamate receptor (mgluR2/3) antagonist. Antidepressant-like action of group II mGlu receptor antagonists does not depend on serotonergic system activation. However, the AMPA receptor seems to play a key role in the an
T70063	GYKI 52466 HCl
	GYKI 52466 is an allosteric AMPA receptor antagonist. It selectively inhibits AMPA-induced inward currents (IC50 = 7.5 µM) over NMDA- or GABA-induced inward currents in primary rat hippocampal neurons at 50 µM but also inhibits kainate-induced inward currents in the same cells (IC50 = 11 µM).2 GYKI 52466 (10 µM) reduces the amplitude of spontaneous excitatory postsynaptic currents (EPSCs) in the same cells. It increases the latency to seizure onset and reduces mortality in a rat model of general...

化合物

AMPA receptor antagonist-2

Cat.No: T61068

Target: iGluR

Cat.No: T7304

Synonym: 二硝基喹酮,FG 9041

Target: GluR, iGluR

DNQX disodium salt

Cat.No: T8459

Synonym: DNQX Disodium

Target: NMDAR, iGluR

Cat.No: T38192

Target: Others

CP-465022 (maleate)

Cat.No: T21875

Cat.No: T28034

Synonym: BCI 632,BCI-632,MGS0039,BCI632

Cat.No: T70063

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