Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10297L |
AMG 487
|
CXCR | Autophagy; GPCR/G Protein; Immunology/Inflammation |
AMG 487 是可口服的选择性趋化因子受体3拮抗剂,对 I-IP-10、I-ITAC 和 MIG 的 IC50 值分别为 8、15 和 36nM。 | |||
T22477 |
(±)-AMG 487
|
Others | Others |
AMG 487 is an effective and selective antagonist of chemokine receptor 3. AMG 487 inhibited CXCR3-mediated cell migration induced by three CXCR3 chemokines, IP-10, ITAC and MIG (IC50: 8, 15 and 36 nM, respectively). | |||
T10297 | AMG 487 (S-enantiomer) | Others | Others |
AMG 487 S-enantiomer is the S enantiomer of AMG 487. AMG 487 is an CXCR3 antagonist. |