Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11762 |
Kira8 Hydrochloride
AMG-18 Hydrochloride |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM. | |||
T11762L |
Kira8
AMG-18 |
IRE1 | Cell Cycle/Checkpoint |
Kira8 (AMG-18) 是一种单选择性 IRE1α 抑制剂,可变构减弱 IRE1α RNase 活性,IC50为 5.9 nM。 |