Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T40099 |
ALV2
|
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ALV2 is a potent and selective Helios degrader compound that binds to the CRBN protein, exhibiting an IC50 value of 0.57 μM. Helios, a zinc-finger transcription factor, plays a crucial role in preserving a stable T reg cell phenotype within the inflammatory tumor microenvironment. |