Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T41345 |
AFMK
Formyl-N-acetyl-5-methoxykynurenamine,Acetyl-N-formyl-5-methoxykynurenamine |
Apoptosis; Free radical scavengers; Antioxidant; Endogenous Metabolite | Apoptosis; Metabolism; oxidation-reduction |
AFMK (Formyl-N-acetyl-5-methoxykynurenamine) 是褪黑激素的活性代谢物,具有抗氧化和自由基清除活性。 AFMK 是一种凋亡调节剂,可提高吉西他滨在 PANC-1 细胞中的抗肿瘤作用。 | |||
T36176 |
AMK (hydrochloride)
|
||
AMK is an active metabolite of the neurohormone melatonin .1,2,3,4It is formed from melatoninviathe metabolic intermediate AFMK that is then deformylated by catalase or formamidase.5,6AMK scavenges singlet oxygenin vitrowhen used at a concentration of 200 μM.1It inhibits the epinephrine- and arachidonic acid-induced production of prostaglandin E2and PGD2in ovine seminal vesicle microsomes in a concentration- and time-dependent manner, as well as LPS-induced increases in COX-2 levels in RAW 264.7... |