Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T10247 |
Adenosine 5'-diphosphoribose sodium
Adenosine 5'-diphosphoribose sodium,ADP ribose sodium |
Endogenous Metabolite; TRP/TRPV Channel; Autophagy | Autophagy; Membrane transporter/Ion channel; Metabolism |
Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种烟酰胺腺嘌呤核苷酸 (NAD+) 的代谢产物,广泛存在于生物体内。Adenosine 5'-diphosphoribose sodium (ADP ribose sodium) 是一种高效的细胞内 Ca2+ 渗透性阳离子 TRPM2 通道激活剂,还可以诱导自噬 (autophagy)。 | |||
T37803 | 8-bromo-Cyclic ADP-Ribose (sodium salt) | ||
Cyclic ADP-ribose (cADP-ribose) is a calcium mobilizing nucleotide that is biosynthesized from NAD+ by cADP-ribose synthases, including CD38. cADP-Ribose appears to activate calcium channels in intracellular membranes, which in turn activate ryanodine receptors. 8-bromo-cADP-Ribose is a stable, cell-permeable analog that blocks calcium release evoked by cADP-ribose in sea urchin egg homogenates with an IC50 value of 1.7 μM. It is commonly used to investigate intracellular signaling through cADP-... |