Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T16557 |
PNU-159682
|
Topoisomerase | DNA Damage/DNA Repair |
PNU-159682 是蒽环类新霉素的代谢产物,是一种 DNA 拓扑异构酶 II 抑制剂,具有出色的细胞毒性。 | |||
T4677 |
MMAD
Monomethylauristatin D,Demethyldolastatin 10,单甲基澳瑞他汀 D,Monomethyl Dolastatin 10 |
Microtubule Associated | Cytoskeletal Signaling |
MMAD (Demethyldolastatin 10) 是一种有效的微管蛋白抑制剂,是抗体药物偶联物中的一种毒素有效载荷。 | |||
T40879 |
7-MAD-MDCPT
|
||
7-MAD-MDCPT, a Camptothecin analog, is a toxin payload in antibody drug conjugates (ADCs). | |||
T40872 |
17-AEP-GA
|
||
17-AEP-GA is a highly effective HSP90 antagonist compound that exhibits potent inhibition against the proliferation, survival, migration, and invasion of glioblastoma cells. Additionally, it demonstrates ADCs Toxin activity. | |||
T11117 |
Duocarmycin MB
|
Others | Others |
Duocarmycin MB can be used against multi-drug resistant cell lines. Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. | |||
T11116 |
Duocarmycin MA
|
Others | Others |
Duocarmycin MA can be used against multi-drug resistant cell lines.Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove. | |||
T10700 |
(+)-CBI-CDPI1
|
Others | Others |
(+)-CBI-CDPI1 is an enhanced functional analog of CC-1065. It is a DNA alkylating agent and an antibody-drug conjugates (ADCs) toxin. | |||
T73948 | Duocarmycin DM | ||
Duocarmycin DM,一种DNA小沟烷基化剂(DNA minor-groove alkylator),作为抗体活性分子结合物(ADCs)的毒素,因其独特结构显示出抗癌活性。 | |||
T75117 | Py-MAA-Val-Cit-PAB-DX8951 | ||
Py-MAA-Val-Cit-PAB-DX8951 是一种参与合成抗体药物偶联物(ADCs)中间体的嘌呤毒素。 |