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Search Results for " abcg2-in-1 "

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抑制剂 & 化合物

1

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Cat. No. Product Name Target Signaling Pathways
T79513 ABCG2-IN-1

BCRP Membrane transporter/Ion channel
ABCG2-IN-1(化合物K2)为Ko143类似物,该口服活性ABCG2抑制剂IC50值为0.13 μM,显示出优良的小鼠体内口服药代动力学特性。
T79514 ABCG2-IN-2

BCRP Membrane transporter/Ion channel
ABCG2-IN-2为一有效ABCG2抑制剂,呈现小鼠良好口服药代动力学性质。适用于研究肿瘤多药耐药(MDR)与红细胞生成性原卟啉症(EPP)。
T36807 Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)

Estradiol 17-(β-D-glucuronide) (E217G) is an estrogen metabolite formed in the liver and subsequently excreted in bile.1It acts as a substrate of the multidrug resistance protein 2 (MRP2; Km= 75 μM), and through MRP2-mediated transport, functions as a cholestatic agent, decreasing bile flow.1,2In addition to binding to the MRP2 transport site, E217G has been shown to bind to an allosteric site that through positive cooperativity activates its own transportviaMRP2 and the transport of other MRP2 ...

化合物

ABCG2-IN-1
Cat.No: T79513
Synonym:
Target: BCRP
ABCG2-IN-2
Cat.No: T79514
Synonym:
Target: BCRP
Estradiol 17-(β-D-Glucuronide) (sodium salt hydrate)
Cat.No: T36807
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T3S1775 Tectochrysin

NSC 80687,Techtochrysine,Techtochrysin,柚木柯因

NF-κB; STAT JAK/STAT signaling; NF-κB; Stem Cells
Tectochrysin (Techtochrysine) 是Alpinia oxyphylla 的主要黄酮类化合物之一,能够抑制NF-κB 活性。

天然产物

Tectochrysin
Cat.No: T3S1775
Synonym: NSC 80687,Techtochrysine,Techtochrysin,柚木柯因
Target: NF-κB, STAT
TargetMol Loading
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