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Cat. No. | Product Name | Target | Signaling Pathways |
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T19327 |
Fodipir
DPDP,福地吡 |
Others | Others |
Fodipir involved in mangafodipir-mediated cytoprotection against 7β-hydroxycholesterol-induced cell death.Fodipir is an active metabolite of mangafodipir. | |||
T36132 |
3β-OH-7-Oxocholenic Acid
|
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3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3 |1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat. Steroids 15(3), 303-326 (1970).|2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick dise... |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1338 |
7Beta-Hydroxycholesterol
|
LDL; Calcium Channel; MAPK | MAPK; Membrane transporter/Ion channel; Metabolism |
7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells. |