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Search Results for " 7-amino-4-methylcoumarin "

14

抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T18909 Ac-DEVD-AMC

AC-ASP-MET-GLN-ASP-AMC,AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN

Caspase Apoptosis; Proteases/Proteasome
Ac-DEVD-AMC (AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN) 是一种 Caspase-3底物。
TD0076 AMCA-H N-succinimidyl ester

7-Hydroxy-4-methylcoumarin-3-acetic acid, succinimidyl ester,7-羟基-4-甲基香豆素-3-乙酸琥珀酰亚胺酯

The amine-reactive AMCA, SE (7-amino-4-methylcoumarin-3-acetic acid, succinimidyl ester) and its conjugates yield blue-fluorescence (approximate excitation/emission maxima ~353/442) that can be used as a contrasting color in multicolor applications.
T36334 Z-VAD-AMC (acetate)

Z-VAD-AMC is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-1 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
T35932 Gly-Arg-AMC (hydrochloride)

Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. |1. Rubach, J.K., Cui, G., Schneck, J.L., et al. The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis. Biochemistry 51(38), 7551-7568 (2012).
T36354 Suc-YVAD-AMC (acetate)

Suc-YVAD-AMC is a fluorogenic substrate for caspase-1. Upon enzymatic cleavage by caspase-1, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-1 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
T36341 Ac-DNLD-AMC

Ac-DNLD-AMC is a fluorogenic caspase-3 substrate. Upon enzymatic cleavage by caspase-3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-3 activity. AMC displays excitation/emission maxima of 340-360 and 440-460 nm, respectively.
T36342 Ac-LEHD-AMC (trifluoroacetate salt)

Ac-LEHD-AMC is a fluorogenic substrate for caspase-9.[1] Upon cleavage by caspase-9, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify caspase-9 activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
T37417 Z-LLE-AMC

Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. Caspase-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLE-AMC is typically used in cell lysates after experimental treatment.
T37420 Ac-ANW-AMC

Ac-ANW-AMC,Ac-Ala-Asn-Trp-AMC

Ac-ANW-AMC is a fluorogenic substrate for the β5i/LMP7 subunit of the 20S immunoproteasome. [1] Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β5i/LMP7 subunit of the 20S immunoproteasome. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. Reference[1]. Winter, M.B., La Greca, F., Arastu-Kapur, S., et al. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. ...
T37421 Ac-PAL-AMC

Ac-PAL-AMC is a fluorogenic substrate for the β1i/LMP2 subunit of the 20S immunoproteasome. Upon cleavage, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify the activity of the β1i/LMP2 subunit of the 20S immunoproteasome. Ac-PAL-AMC is selective for the immunoproteasome over the constitutive proteasome. AMC displays excitation/emission maxima of 351/430 nm, respectively.
T36346 Ac-VEID-AMC (ammonium acetate salt)

Ac-VEID-AMC is a fluorogenic substrate based on the caspase-6 cleavage site in lamin A at amino acids VEID during apoptosis.1It has also been reported to be cleaved by related proteases, including caspase-8.2Caspase activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. 1.Talanian, R.V., Quinlan, C., Trautz, S., et al.Substrate specificities of caspase family proteasesJ. Biol. Chem.272(15)9...
T37418 Z-LLL-AMC

Z-LLL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core. Chymotrypsin-like activity can be quantified by fluorescent detection of free AMC (also known as 7-amino-4-methylcoumarin), which is excited at 340-360 nm and emits at 440-460 nm. Z-LLL-AMC is typically used in cell lysates after experimental treatment.
T36105 coumarin-SAHA

coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA

Suberoylanilide hydroxamic acid (SAHA) is a class I and class II histone deacetylase (HDAC) inhibitor that binds directly to the catalytic site of the enzyme thereby blocking substrate access. [1] coumarin-Suberoylanilide hydroxamic acid (c-SAHA) is a SAHA derivative where the anilino cap" group is replaced by 7-amino-4-methylcoumarin to produce a fluorescent probe that competitively binds HDAC. [2] The fluorescence excitation and emission maxima of free c-SAHA is 325 and 400 nm
T37053 Z-(L-Arg)-AMC (hydrochloride)

Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H.1,2Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify trypsin, cathepsin B, and cathepsin H activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. 1.Zimmerman, M., Ashe, B., Yurewicz, E.C., et al.Sensitive assays for trypsin, elastase, and chymotrypsin using new fluorogenic substrat...

化合物

Ac-DEVD-AMC
Cat.No: T18909
Synonym: AC-ASP-MET-GLN-ASP-AMC,AC-ASP-MET-GLN-ASP-7-AMINO-4-METHYLCOUMARIN
Target: Caspase
AMCA-H N-succinimidyl ester
Cat.No: TD0076
Synonym: 7-Hydroxy-4-methylcoumarin-3-acetic acid, succinimidyl ester,7-羟基-4-甲基香豆素-3-乙酸琥珀酰亚胺酯
Target:
Z-VAD-AMC (acetate)
Cat.No: T36334
Synonym:
Target:
Gly-Arg-AMC (hydrochloride)
Cat.No: T35932
Synonym:
Target:
Suc-YVAD-AMC (acetate)
Cat.No: T36354
Synonym:
Target:
Ac-DNLD-AMC
Cat.No: T36341
Synonym:
Target:
Ac-LEHD-AMC (trifluoroacetate salt)
Cat.No: T36342
Synonym:
Target:
Z-LLE-AMC
Cat.No: T37417
Synonym:
Target:
Ac-ANW-AMC
Cat.No: T37420
Synonym: Ac-ANW-AMC,Ac-Ala-Asn-Trp-AMC
Target:
Ac-PAL-AMC
Cat.No: T37421
Synonym:
Target:
Ac-VEID-AMC (ammonium acetate salt)
Cat.No: T36346
Synonym:
Target:
Z-LLL-AMC
Cat.No: T37418
Synonym:
Target:
coumarin-SAHA
Cat.No: T36105
Synonym: coumarin-Suberoylanilide Hydroxamic Acid,coumarin-SAHA
Target:
Z-(L-Arg)-AMC (hydrochloride)
Cat.No: T37053
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN1328 7-Amino-4-methylcoumarin-3-acetic acid

7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin

Others Others
7-Amino-4-methylcoumarin-3-acetic acid (7-Amino-4-methylcoumarin) 是荧光蛋白质标记剂,能够被紫外光(350 nm) 激活,可在蓝色区域 (440-460 nm) 发光。

天然产物

7-Amino-4-methylcoumarin-3-acetic acid
Cat.No: TN1328
Synonym: 7-氨基-4-甲基-3-香豆素醋酸,7-Amino-4-methylcoumarin
Target: Others
TargetMol Loading
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