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Cat. No. Product Name Target Signaling Pathways
T0075 Nicorandil

SG-75,尼可地尔

Potassium Channel Membrane transporter/Ion channel
Nicorandil (SG-75) 是一种有效的钾通道激活剂,靶向血管核苷二磷酸依赖性 K+通道和心脏 ATP 敏感 K+通道 (KATP)。Nicorandil 是一种烟酰胺酯,具有血管舒张和心脏保护作用,并具有治疗心绞痛和缺血性心脏病的潜力。
T71402 Nicorandil-d4

Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =...

化合物

Nicorandil
Cat.No: T0075
Synonym: SG-75,尼可地尔
Target: Potassium Channel
Nicorandil-d4
Cat.No: T71402
Synonym:
Target:
TargetMol Loading
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