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Search Results for " 4ebp1 "

Targets Recommended: mTOR

4

抑制剂 & 化合物

1

化合物库

2

重组蛋白

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Cat. No.	Product Name
L1300	PI3K/Akt/mTOR 化合物库		420 compounds
	420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合，用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选；

化合物库

PI3K/Akt/mTOR 化合物库

Cat.No: L1300

Compounds: 420

Cat. No.	Product Name	Target	Signaling Pathways
T14886	Cbz-B3A	mTOR	PI3K/Akt/mTOR signaling
	Cbz-B3A 是一种具有现在性的 mTORC1 信号转导抑制剂，抑制 eIF4E 结合蛋白 1 （4EBP1）的磷酸化并阻断 68% 的翻译。
T60675L	AMPK activator 2 hydrochloride( 2410961-69-0 Free base) AMPK activator 2 hydrochloride( 2410961-69-0 Free base)	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	AMPK activator 2 hydrochloride 是一种含氟氯胍衍生物，可上调 AMPK 信号通路并下调 mTOR/4EBP1/p70S6K。AMPK activator 2 hydrochloride 抑制人类癌细胞系 (UMUC3、T24、A549) 的增殖和迁移。
T74283	RMC-4627
	RMC-4627是一种选择性的mTORC1抑制剂，可激活4EBP1并抑制肿瘤生长。
T60675	AMPK activator 2	AMPK	Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
	AMPK activator 2 是一种含氟氯胍衍生物，具有潜在的抗癌活性，可上调 AMPK 信号通路并下调 mTOR/4EBP1/p70S6K，对人类癌细胞系 (UMUC3、T24、A549) 的增殖和迁移有抑制作用。

化合物

Cat.No: T14886

Target: mTOR

AMPK activator 2 hydrochloride( 2410961-69-0 Free base)

Cat.No: T60675L

Synonym: AMPK activator 2 hydrochloride( 2410961-69-0 Free base)

Target: AMPK

Cat.No: T74283

AMPK activator 2

Cat.No: T60675

Target: AMPK

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01769	4EBP1 Protein, Human, Recombinant (His) 4E-BP1,eukaryotic translation initiation f...	Human	E. coli
	The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcription factor activating transcription factor-4 (ATF4), a master regulator of gene expression in stress responses. 4E-BP1 is characterized by its capacity to bind specifically to eIF4E and inhibit its interaction with eIF4G. Phosphorylation of 4E-BP1 regulates eIF4E availability, a...
TMPY-06821	THRB Protein, Human, Recombinant (His) THRB1,GRTH,THR1,ERBA2,C-ERBA-2,THRB2,thyro...	Human	E. coli
	Thyroid hormone receptor beta (THRB), also known as TRbeta and NR1A2, belongs to the nuclear hormone receptor family. Featuring an N-terminal transactivation domain, a central DNA-binding domain, and a hormone/ligand-binding domain, THRB isoform 1/2 expression localizes predominately to the liver and pituitary, respectively. THRB regulates the feedback of T3-dependent thyrotropin-stimulating hormone (TSH) transcription in the pituitary by binding to thyroid hormone (TH) response elements present...

重组蛋白

4EBP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01769

Species: Human

Expression System: E. coli

THRB Protein, Human, Recombinant (His)

Cat.No: TMPY-06821

Species: Human

Expression System: E. coli

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