Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13764 |
Lycopodine
|
Lipoxygenase; Caspase | Apoptosis; Metabolism; Proteases/Proteasome |
Lycopodine, a bioactive compound derived from Lycopodium clavatum spores, effectively inhibits the proliferation of HeLa cells through the induction of apoptosis. This process is mediated by caspase-3 activation. In refractory prostate cancer cells, Lycopodine triggers apoptosis by modulating 5-lipoxygenase and depolarizing the mitochondrial membrane potential, without altering p53 activity. |