Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7465 |
4-Methylbenzylidene camphor
Enzacamene,4-甲基苄亚基樟脑,3-(4-甲基苯亚甲基)樟脑,4-MBC |
AChE | Neuroscience |
4-Methylbenzylidene camphor 是有机的樟脑衍生物,应用于化妆品行业,具有保护皮肤抵抗紫外线(特别是紫外线B 辐射)的能力。 | |||
T0666 |
4-Chlorosalicylic acid
4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid,4-氯水杨酸 |
Tyrosinase; Antibacterial; Antibiotic; Antifungal | Microbiology/Virology; Proteases/Proteasome |
4-Chlorosalicylic acid (4-Chloro-2-hydroxybenzoic acid, 4-chloro salicylic acid) 是一种药物中间体。它抑制单酚酶和二苯酚酶活性,IC50值分别为1.89 mM 和1.10 mM。 它有抗菌活性,抑制大肠杆菌的MIC 为250 μg/mL,MBC 为500 μg/mL。 | |||
T36648 | Tucatinib hemiethanolate | ||
Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-fold selective for HER2 versus EGFR in cell-based assays. Tucatinib selectively inhibits the receptor tyrosine kinase HER2 relative to EGFR[1].Tucatinib blocks proliferation and the phosphorylation of HER2 and its downstream effector, Akt in HER2 overexpressing cell lines. In the ... |