Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6699 |
Tempol
TMPN,Tanol,4-Hydroxy-TEMPO,阻聚剂701 |
Reactive Oxygen Species; ROS; Autophagy | Autophagy; Immunology/Inflammation; Metabolism; NF-κB |
Tempol (Tanol) 是一种超氧化物歧化酶类似物,可有效中和活性氧,具有抗炎、神经保护和镇痛作用。 | |||
T35965 |
MitoTEMPOL
|
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MitoTEMPOL is a mitochondria-targeting superoxide dismutase mimetic that reduces mitochondrial O2- to H2O2. Like the related compound MitoTEMPO , MitoTEMPOL combines an antioxidant moiety (here, TEMPOL, also known as 4-hydroxy-TEMPO) with the lipophilic cation triphenylphosphonium, which allows it to pass through lipid bilayers and accumulate in mitochondria. MitoTEMPOL has been used to elucidate the role of mitochondria-derived superoxide in mitochondrial, cellular, and whole animal signaling. |