Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T64113 |
J-2156 TFA
|
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J-2156 TFA 是一种选择性的、高效的生长抑素受体 4 型 (SST4) 激动剂,能够作用于人 SST4 受体 (IC50: 0.05 nM) 和大鼠 SST4 受体 (IC50: 0.07 nM)。J-2156 TFA 表现出抗炎活性,能够缓解大鼠同侧后爪的机械性异常性疼痛和机械性痛觉过敏。 | |||
T11700 |
J-2156
|
Others | Others |
The ED50 of J-2156 in rats for the relief of mechanical allodynia and mechanical hyperalgesia in the ipsilateral hindpaws was 3.7 and 8.0 mg/kg, respectively. J-2156 is a high potent, selective somatostatin receptor type 4 (SST4 receptor) agonist with IC5 |